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Literature detail

Genome sequence conservation of Hendra virus isolates during spillover to horses, Australia.

Glenn A Marsh1 Shawn Todd Adam Foord Eric Hansson Kelly Davies Lynda Wright Chris Morrissy Kim Halpin Deborah Middleton Hume E Field Peter Daniels Lin-Fa Wang
Affiliations 1 institutions
  1. Australian Animal Health Laboratory, Geelong, Victoria, Australia. [email protected]
PMID 21029540 2010 Emerg Infect Dis eng ppublish
PubMed DOI Browse context

Article

Publication summary

Bat-to-horse transmission of Hendra virus has occurred at least 14 times. Although clinical signs in horses have differed, genome sequencing has demonstrated little variation among the isolates. Our sequencing of 5 isolates from recent Hendra virus outbreaks in horses found no correlation between sequences and time or geographic location of outbreaks.

Chiroptera Genome, Viral Animals Australia Disease Outbreaks Hendra Virus Henipavirus Infections Horse Diseases Horses Phylogeny

Structured evidence records

Evidence records

2 total
Genomic Evolution 1 records
Genomic Evolution Extraction confidence 0.90
Key finding

Sequencing of Hendra virus isolates from horse spillover events in Australia showed highly conserved genomes across outbreaks.

Virus
HeV
Location
Not specified
Supporting text

Genome sequencing has demonstrated little variation among the isolates. Our sequencing of 5 isolates from recent Hendra virus outbreaks in horses found no correlation between sequences and time or geographic location of outbreaks.

Genes or proteins
whole genome
Analysis methods
genome sequencing; phylogenetic analysis
Spillover Event 1 records
Spillover Event Extraction confidence 0.98
Key finding

Hendra virus has spilled over from bats to horses multiple times in Australia.

Virus
HeV
Location
Australia Australia
Supporting text

Bat-to-horse transmission of Hendra virus has occurred at least 14 times.

Method
genome sequencing
Study design
outbreak investigation
Transmission direction
animal-to-human
Geographic raw
Australia
Country inferred
Australia