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Literature detail

Unusual case of severe fever with thrombocytopenia syndrome showing clinical manifestations in a companion dog.

So-Jeong Nam1 Ye-In Oh2 Hyun-Jung Kim3 Doo-Sung Cheon4 Sung-Jun Noh5 Yeon-Jung Hong1
Affiliations 5 institutions
  1. Western Animal Medical Center, Seoul, South Korea.
  2. Chungnam National University, Daejeon, South Korea.
  3. Animal and Plant Quarantine Agency, Gimcheon, South Korea.
  4. Postbio Inc., Guri-si, South Korea.
  5. Naeum Animal Medical Center, Cheongju, South Korea.
PMID 32279458 2020 Vet Med Sci eng ppublish
PubMed DOI Browse context

Article

Publication summary

Severe fever with thrombocytopenia syndrome (SFTS) virus is an emerging zoonotic virus in East Asia. However, SFTS virus (SFTSV) has not been reported to cause clinical infection in companion dogs to date. We report the case of a 4-year-old companion dog that presented with fever, vomiting, leukocytopenia and thrombocytopenia at a veterinary hospital in the Republic of Korea. It was diagnosed with SFTS, which was confirmed using real-time reverse transcription PCR, sequencing and an indirect immunofluorescence assay, and recovered after supportive care. Further studies are required to investigate SFTSV infection in companion animals, living in close contact with humans, as well as animal-to-human transmission.

dog Huaiyangshan banyangvirus Republic of Korea severe fever with thrombocytopenia syndrome tick Animals Dog Diseases Dogs Fever Leukopenia Male Phlebovirus Republic of Korea Severe Fever with Thrombocytopenia Syndrome Thrombocytopenia Treatment Outcome Vomiting

Structured evidence records

Evidence records

1 total
Spillover Event 1 records
Spillover Event Extraction confidence 0.95
Key finding

Severe fever with thrombocytopenia syndrome virus infection was confirmed in a companion dog, representing human-to-animal spillback in the Republic of Korea.

Virus
SFTSV
Location
South Korea South Korea
Supporting text

We report the case of a 4-year-old companion dog that presented with fever, vomiting, leukocytopenia and thrombocytopenia at a veterinary hospital in the Republic of Korea. It was diagnosed with SFTS, which was confirmed using real-time reverse transcription PCR, sequencing and an indirect immunofluorescence assay.

Method
real-time reverse transcription PCR; sequencing; indirect immunofluorescence assay
Study design
case report
Transmission direction
human-to-animal
Geographic raw
Republic of Korea
Country inferred
Republic of Korea