Possible Bat Origin of Severe Acute Respiratory Syndrome Coronavirus 2.

Susanna K P Lau Hayes K H Luk Antonio C P Wong Kenneth S M Li Longchao Zhu Zirong He Joshua Fung Tony T Y Chan Kitty S C Fung Patrick C Y Woo

Abstract

We showed that severe acute respiratory syndrome coronavirus 2 is probably a novel recombinant virus. Its genome is closest to that of severe acute respiratory syndrome-related coronaviruses from horseshoe bats, and its receptor-binding domain is closest to that of pangolin viruses. Its origin and direct ancestral viruses have not been identified.

bats 46 coronavirus disease 15 COVID-19 467 genomic analysis 3 recombinant virus 0 recombination 40 respiratory infections 30 SARS-CoV-2 550 severe acute respiratory syndrome coronavirus 2 20 viruses 117 zoonoses 477 Animals 1948 Betacoronavirus 78 Chiroptera 371 Phylogeny 805 Recombination, Genetic 59 SARS-CoV-2 453

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