NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P.R. China.
Emerging infectious diseases significantly threaten global public health and socioeconomic security. The majority of emerging infectious disease outbreaks are caused by zoonotic/vector-borne viruses. Bats and rodents are the two most important reservoir hosts of many zoonotic viruses that can cross species barriers to infect humans, whereas mosquitos and ticks are well-established major vectors of many arboviral diseases. Moreover, some emerging zoonotic diseases require a vector to spread or are intrinsically vector-borne and zoonotically transmitted. In this study, we present a newly upgraded database of zoonotic and vector-borne viruses designated ZOVER (http://www.mgc.ac.cn/ZOVER). It incorporates two previously released databases, DBatVir and DRodVir, for bat- and rodent-associated viruses, respectively, and further collects up-to-date knowledge on mosquito- and tick-associated viruses to establish a comprehensive online resource for zoonotic and vector-borne viruses. Additionally, it integrates a set of online visualization tools for convenient comparative analyses to facilitate the discovery of potential patterns of virome diversity and ecological characteristics between/within different viral hosts/vectors. The ZOVER database will be a valuable resource for virologists, zoologists and epidemiologists to better understand the diversity and dynamics of zoonotic and vector-borne viruses and conduct effective surveillance to monitor potential interspecies spillover for efficient prevention and control of future emerging zoonotic diseases.
Bats and rodents are the two most important reservoir hosts of many zoonotic viruses that can cross species barriers to infect humans, whereas mosquitos and ticks are well-established major vectors of many arboviral diseases.
Reservoir EcologyExtraction confidence 0.80
Key finding
Rodents are identified as major reservoir hosts contributing to the maintenance and ecology of zoonotic viruses.
Bats and rodents are the two most important reservoir hosts of many zoonotic viruses that can cross species barriers to infect humans, whereas mosquitos and ticks are well-established major vectors of many arboviral diseases.
Reservoir EcologyExtraction confidence 0.80
Key finding
Mosquitos are described as major vectors involved in arboviral disease ecology.
Bats and rodents are the two most important reservoir hosts of many zoonotic viruses that can cross species barriers to infect humans, whereas mosquitos and ticks are well-established major vectors of many arboviral diseases.
Reservoir EcologyExtraction confidence 0.80
Key finding
Ticks are identified as important vectors that maintain and transmit arboviral diseases.
Bats and rodents are the two most important reservoir hosts of many zoonotic viruses that can cross species barriers to infect humans, whereas mosquitos and ticks are well-established major vectors of many arboviral diseases.
Zoonotic Surveillance4 records
Zoonotic SurveillanceExtraction confidence 0.95
Key finding
ZOVER compiles surveillance data on viruses associated with bats, rodents, mosquitoes, and ticks into an integrated resource for zoonotic and vector-borne virus monitoring.
It incorporates two previously released databases, DBatVir and DRodVir, for bat- and rodent-associated viruses, respectively, and further collects up-to-date knowledge on mosquito- and tick-associated viruses to establish a comprehensive online resource for zoonotic and vector-borne viruses.
Zoonotic SurveillanceExtraction confidence 0.95
Key finding
Rodent-associated viral surveillance data are included in the ZOVER database to facilitate monitoring of zoonotic viruses.
It incorporates two previously released databases, DBatVir and DRodVir, for bat- and rodent-associated viruses, respectively, and further collects up-to-date knowledge on mosquito- and tick-associated viruses to establish a comprehensive online resource for zoonotic and vector-borne viruses.
Zoonotic SurveillanceExtraction confidence 0.95
Key finding
Mosquito-associated viral data are included in ZOVER to support surveillance of vector-borne zoonotic viruses.
It incorporates two previously released databases, DBatVir and DRodVir, for bat- and rodent-associated viruses, respectively, and further collects up-to-date knowledge on mosquito- and tick-associated viruses to establish a comprehensive online resource for zoonotic and vector-borne viruses.
Zoonotic SurveillanceExtraction confidence 0.95
Key finding
Tick-associated viral data are included in ZOVER for surveillance of vector-borne zoonotic viruses.
It incorporates two previously released databases, DBatVir and DRodVir, for bat- and rodent-associated viruses, respectively, and further collects up-to-date knowledge on mosquito- and tick-associated viruses to establish a comprehensive online resource for zoonotic and vector-borne viruses.
Citation context
References
24 references
Reference network
Force-directed citation graph. OmniVira-indexed references are prioritized and recursively expanded up to three steps.
