Novel Hendra Virus Variant Circulating in Black Flying Foxes and Grey-Headed Flying Foxes, Australia.
Alison J Peel
Claude Kwe Yinda
Edward J Annand
Adrienne S Dale
Peggy Eby
John-Sebastian Eden
Devin N Jones
Maureen K Kessler
Tamika J Lunn
Tim Pearson
Jonathan E Schulz
Ina L Smith
Vincent J Munster
Raina K Plowright
Bat One Health Group
A novel Hendra virus variant, genotype 2, was recently discovered in a horse that died after acute illness and in Pteropus flying fox tissues in Australia. We detected the variant in flying fox urine, the pathway relevant for spillover, supporting an expanded geographic range of Hendra virus risk to horses and humans.
Cross Species TransmissionExtraction confidence 0.85
Key finding
A novel Hendra virus variant circulates between black flying foxes and grey-headed flying foxes in Australia, indicating cross-species viral transmission among flying fox species.
A novel Hendra virus variant, genotype 2, was recently discovered ... in Pteropus flying fox tissues in Australia. The title specifies circulation in black flying foxes and grey-headed flying foxes.
Method
virus detection
Study design
field surveillance
Transmission direction
animal-to-animal
Geographic raw
Australia
Country inferred
Australia
Genomic Evolution1 records
Genomic EvolutionExtraction confidence 0.80
Key finding
A distinct genotype 2 variant of Hendra virus was identified from sequences derived from a horse and Pteropus flying foxes in Australia.
A novel Hendra virus variant, genotype 2, was recently discovered in a horse that died after acute illness and in Pteropus flying fox tissues in Australia.
Analysis methods
genotype identification
Reservoir Ecology1 records
Reservoir EcologyExtraction confidence 0.75
Key finding
Hendra virus variant genotype 2 was detected in black flying foxes and grey-headed flying foxes in Australia, indicating these bats serve as reservoir hosts and that virus shedding through urine contributes to spillover risk.
A novel Hendra virus variant, genotype 2, was recently discovered in a horse that died after acute illness and in Pteropus flying fox tissues in Australia. We detected the variant in flying fox urine, the pathway relevant for spillover, supporting an expanded geographic range of Hendra virus risk to horses and humans.
Method
virus detection
Sample type
tissues; urine
Geographic raw
Australia
Country inferred
Australia
Spillover Event1 records
Spillover EventExtraction confidence 0.90
Key finding
Hendra virus genotype 2 was detected in both a horse that died after acute illness and in flying foxes, indicating an animal-to-horse spillover of the virus in Australia.
A novel Hendra virus variant, genotype 2, was recently discovered in a horse that died after acute illness and in Pteropus flying fox tissues in Australia. We detected the variant in flying fox urine, the pathway relevant for spillover.
Transmission direction
animal-to-human
Geographic raw
Australia
Country inferred
Australia
Zoonotic Surveillance1 records
Zoonotic SurveillanceExtraction confidence 0.95
Key finding
Hendra virus variant genotype 2 was detected in flying fox urine in Australia, reflecting active surveillance of bat reservoirs for zoonotic spillover risk.
We detected the variant in flying fox urine, the pathway relevant for spillover, supporting an expanded geographic range of Hendra virus risk to horses and humans.
Sample type
urine
Geographic raw
Australia
Country inferred
Australia
Citation context
References
13 references
Reference network
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