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Literature detail

Molecular epidemiological surveillance of circovirus in avian and mammalian species on the Brazilian coast.

Ana Julia Chaves Gomes1 Yasmin Luisa Neves Lemes Garcia1 Dayla Bott Geraldini1 Camila Domit2 Fábio Henrique de Lima2 João Pessoa Araújo3 Juliana Schons Gularte4 Micheli Filippi4 Vyctoria Malayhka de Abreu Góes Pereira4 Meriane Demoliner4 Alexandre Sita4 Fernando Rosado Spilki4 Marília de Freitas Calmon1 Paula Rahal1 Vivaldo Gomes da Costa5
Affiliations 5 institutions
  1. Genomics Laboratory, Department of Biology, São Paulo State University (UNESP), São José do Rio Preto, 15054-000, SP, Brazil.
  2. Ecology and Conservation Laboratory, Federal University of Paraná (UFPR), 83255-976, PR, Pontal do Paraná, Brazil.
  3. Veterinary Molecular Diagnostic Laboratory, Institute of Biotechnology, São Paulo State University (UNESP), Botucatu, 01049-010, SP, Brazil.
  4. Molecular Microbiology Laboratory, Feevale University, Novo Hamburgo, 93525-075, RS, Brazil.
  5. Genomics Laboratory, Department of Biology, São Paulo State University (UNESP), São José do Rio Preto, 15054-000, SP, Brazil. [email protected].
PMID 42209892 2026 Arch Virol eng epublish
PubMed DOI Browse context

Article

Publication summary

Circoviruses (CVs) infect diverse mammals, birds, and freshwater fish and are linked to diseases causing major economic losses. Despite being well studied in psittacines, their circulation in other avian groups and mammals is poorly understood. We conducted molecular surveillance of CVs in migratory birds and mammals along the Paraná coast, southern Brazil. Sterna hirundinacea specimen tested positive by Nested-PCR for GullCV. In the GullCV-infected bird, histopathology revealed nonspecific lesions, including marked splenic lymphoid atrophy, cachexia-related changes, acute tubular necrosis, and generalized congestion. Sanger sequencing revealed 83% nucleotide identity with CV sequences previously reported in gulls from the United States, which was consistent with results obtained by NGS and Rep-based phylogenetic analysis. These findings contribute to the understanding of CV diversity, distribution, and host range.

Bird Diseases Circoviridae Infections Circovirus Animals Birds Brazil Epidemiological Monitoring Mammals Molecular Epidemiology Phylogeny Sequence Analysis, DNA

Structured evidence records

Evidence records

1 total
Zoonotic Surveillance 1 records
Zoonotic Surveillance Extraction confidence 0.88
Key finding

Circovirus (GullCV) was detected in a Sterna hirundinacea specimen during molecular surveillance of birds and mammals on the Brazilian coast, showing 83% nucleotide identity with circoviruses previously found in gulls.

Virus
Circovirus
Host
Aves Mammalia
Location
Paraná coast southern Brazil, Brazil
Supporting text

We conducted molecular surveillance of CVs in migratory birds and mammals along the Paraná coast, southern Brazil. Sterna hirundinacea specimen tested positive by Nested-PCR for GullCV. ... Sanger sequencing revealed 83% nucleotide identity with CV sequences previously reported in gulls from the United States.

Method
Nested-PCR | Sanger sequencing | NGS | Rep-based phylogenetic analysis
Study design
molecular surveillance
Transmission direction
animal reservoir only
Event type
molecular surveillance in wild birds and mammals
Geographic raw
Paraná coast | southern Brazil
Country inferred
BRA
Genes or proteins
Rep