Myodes rufocanus bedfordiae

Evidence-grounded Research Brief · Past 3 months 4

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Publication date	Category / type	Key finding	PMID
2026-06-30	Zoonotic Surveillance Virus Isolation	Infectious Hokkaido virus (HOKV) was successfully recovered from oral swabs, urine, and feces of wild Myodes rufocanus bedfordiae captured in Tobetsu, Hokkaido, Japan.	42377061
2026-06-30	Zoonotic Surveillance Viral Detection	Hokkaido virus (HOKV) RNA and antigens were detected in lungs, kidneys, and spleen of wild gray red-backed voles (Myodes rufocanus bedfordiae) captured in Tobetsu, Hokkaido, Japan.	42377061
2026-06-30	Zoonotic Surveillance Serological Evidence	Some Myodes rufocanus bedfordiae voles captured in Tobetsu, Hokkaido, Japan were negative for anti-HOKV IgG but had low neutralizing antibody titers and IgG avidity, consistent with acute Hokkaido virus (HOKV) infection.	42377061
2026-06-30	Zoonotic Surveillance Serological Evidence	Wild Myodes rufocanus bedfordiae voles captured in Tobetsu, Hokkaido, Japan showed high antibody titers and high IgG avidities to Hokkaido virus (HOKV), indicating persistent infection.	42377061

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