Recent evidence findings
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
2 source articles
2 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-08 | Experimental Infection Pathogenicity Experiment | In a mouse model, the NelB strain of Nelson Bay orthoreovirus did not exhibit a virulent phenotype, in contrast to the virulent MB strain. | 42546031 |
| 2026-08 | Functional Mechanism Molecular Adaptation | Among S1-encoded proteins, the structural protein σC determines in vivo virulence differences between NBV strains, whereas FAST and p17 do not. | 42546031 |
| 2026-08 | Functional Mechanism Molecular Adaptation | The S1 gene segment of Nelson Bay orthoreovirus correlates with strain-specific virulent phenotypes identified by reverse genetics. | 42546031 |
| 2026-08 | Functional Mechanism Molecular Adaptation | The middle body domain of NBV σC, rather than the C-terminal head domain, underlies differences in virulent phenotypes. | 42546031 |
| 2026-05 | Experimental Infection Pathogenicity Experiment | N57-based monoreassortant PRVs carrying the S1 or S2 segment of MB exhibited enhanced virulence and lower survival rates in mice compared with wild-type N57. | 42189872 |
| 2026-05 | Experimental Infection Pathogenicity Experiment | MB-based monoreassortant PRVs carrying the S1 or S2 genomic segment from N57 showed attenuated virulence with reduced lung viral loads and cytokine gene expression in mice. | 42189872 |
| 2026-05 | Zoonotic Surveillance Virus Isolation | The Pteropine orthoreovirus strain Nachunsulwe-57 (N57) was isolated from a Zambian fruit bat. | 42189872 |
| 2026-05 | Experimental Infection Pathogenicity Experiment | PRV strain Nachunsulwe-57 (N57) exhibited low virulence compared with the human-derived strain Miyazaki-Bali/2007 (MB) in laboratory mice. | 42189872 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
1 source articles
1 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-08 | Experimental Infection Pathogenicity Experiment | In a mouse model, the NelB strain of Nelson Bay orthoreovirus did not exhibit a virulent phenotype, in contrast to the virulent MB strain. | 42546031 |
| 2026-08 | Functional Mechanism Molecular Adaptation | Among S1-encoded proteins, the structural protein σC determines in vivo virulence differences between NBV strains, whereas FAST and p17 do not. | 42546031 |
| 2026-08 | Functional Mechanism Molecular Adaptation | The S1 gene segment of Nelson Bay orthoreovirus correlates with strain-specific virulent phenotypes identified by reverse genetics. | 42546031 |
| 2026-08 | Functional Mechanism Molecular Adaptation | The middle body domain of NBV σC, rather than the C-terminal head domain, underlies differences in virulent phenotypes. | 42546031 |
No publication-dated literature was found for this virus in this window.
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
0 source articles
0 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| No publication-dated evidence in this window. | |||