Recent evidence findings
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
6 source articles
7 hosts
1 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-09-23 | Functional Mechanism Molecular Adaptation | Host RBP NONO upregulates the MERS-CoV entry receptor DPP4 via epigenetic regulation, enabling MERS-CoV replication and entry. | 42818199 |
| 2026-09-23 | Functional Mechanism Receptor Usage | MERS-CoV uses DPP4 (CD26) as the major cellular receptor required for attachment and entry. | 42818199 |
| 2026-09-16 | Functional Mechanism Receptor Usage | Aminopeptidase N (APN) functions as a receptor for hedgehog merbecoviruses. | 42749891 |
| 2026-09-16 | Experimental Infection Host Range Experiment | Hedgehog merbecoviruses could not use human aminopeptidase N (APN) and showed restricted use across 30 mammalian APN orthologues in receptor-entry assays. | 42749891 |
| 2026-09-16 | Experimental Infection Host Range Experiment | Hedgehog coronavirus spike pseudotypes were more infectious when produced at 33 °C than at 37 °C. | 42749891 |
| 2026-09-16 | Functional Mechanism Receptor Usage | Electron cryomicroscopy defined a distinct spike–APN interface for hedgehog merbecoviruses, explaining restricted cross-species receptor usage. | 42749891 |
| 2026-09-16 | Functional Mechanism Receptor Usage | APN receptor usage by hedgehog merbecoviruses was validated using VSV-based pseudotype entry and protein binding assays. | 42749891 |
| 2026-09-08 | Zoonotic Surveillance Serological Evidence | Pre-2019 human sera from wildlife hunter communities in Guinea showed IgG cross-reactivity to SARS-CoV, SARS-CoV-2, and MERS-CoV spike antigens. | 42797820 |
| 2026-09-08 | Zoonotic Surveillance Serological Evidence | A subgroup of human sera from Guinea showed strong binding to both SARS-CoV and MERS-CoV receptor binding domains. | 42797820 |
| 2026-08-21 | Experimental Infection Host Range Experiment | RhGB01 and BM48-31 spikes utilized only Rhinolophus blasii ACE2 in entry assays. | 42627230 |
| 2026-07-29 | Zoonotic Surveillance Viral Detection | A MERS-related coronavirus (Betacoronavirus cameli) was detected by nested RT-PCR and HTS in a rectal swab from one Molossus molossus bat in southern Brazil (1/65, 1.5%). | 42525174 |
| 2026-07-29 | Genomic Evolution Phylogenetic Evolution | Phylogenetic reconstruction of five genomic contigs placed the detected Betacoronavirus cameli within Merbecovirus and showed close relationship to MERS-CoV strains from bats and dromedary camels. | 42525174 |
| 2026-07 | Experimental Infection Host Range Experiment | Seasonal influenza A H1N1, H3N2, influenza B, MERS-CoV, and SARS-CoV productively replicated and infected human bronchial tissues in an ex vivo model. | 42397692 |
| 2026-07 | Experimental Infection Pathogenicity Experiment | In an in vitro human alveolar model, HPAI H5N1, H7N9, MERS-CoV, and SARS-CoV caused more severe impairment of alveolar fluid clearance than seasonal H1N1, H3N2, and influenza B viruses. | 42397692 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
2 source articles
2 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-09-23 | Functional Mechanism Molecular Adaptation | Host RBP NONO upregulates the MERS-CoV entry receptor DPP4 via epigenetic regulation, enabling MERS-CoV replication and entry. | 42818199 |
| 2026-09-23 | Functional Mechanism Receptor Usage | MERS-CoV uses DPP4 (CD26) as the major cellular receptor required for attachment and entry. | 42818199 |
| 2026-09-16 | Functional Mechanism Receptor Usage | Aminopeptidase N (APN) functions as a receptor for hedgehog merbecoviruses. | 42749891 |
| 2026-09-16 | Experimental Infection Host Range Experiment | Hedgehog merbecoviruses could not use human aminopeptidase N (APN) and showed restricted use across 30 mammalian APN orthologues in receptor-entry assays. | 42749891 |
| 2026-09-16 | Experimental Infection Host Range Experiment | Hedgehog coronavirus spike pseudotypes were more infectious when produced at 33 °C than at 37 °C. | 42749891 |
| 2026-09-16 | Functional Mechanism Receptor Usage | Electron cryomicroscopy defined a distinct spike–APN interface for hedgehog merbecoviruses, explaining restricted cross-species receptor usage. | 42749891 |
| 2026-09-16 | Functional Mechanism Receptor Usage | APN receptor usage by hedgehog merbecoviruses was validated using VSV-based pseudotype entry and protein binding assays. | 42749891 |
No publication-dated literature was found for this virus in this window.
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
0 source articles
0 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| No publication-dated evidence in this window. | |||