Recent evidence findings
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
6 source articles
2 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-10 | Zoonotic Surveillance Virus Isolation | Fifty-six influenza A viruses were isolated from swine in Vietnam during 2020–2024, comprising 21 H1N1, 31 H1N2, and 4 H3N2 isolates. | 42811277 |
| 2026-09-29 | Genomic Evolution Phylogenetic Evolution | Phylogenetic analysis indicates that HA A227E and NA S369N substitutions were acquired in swine prior to the emergence of H1N1pdm09 in humans. | 42776754 |
| 2026-09-29 | Functional Mechanism Molecular Adaptation | In H1N1pdm09-related swine viruses, HA A227E reduces receptor binding and NA S369N in the 2SBS reduces NA cleavage, jointly adjusting the HA–NA balance linked to host-range adaptation before the 2009 pandemic emergence. | 42776754 |
| 2026-09-10 | Zoonotic Surveillance Virus Isolation | Six H1N1 viruses belonging to the G4 genotype were isolated from pigs with respiratory disease in six Chinese provinces during 2023–2025. | 42797971 |
| 2026-09-10 | Genomic Evolution Phylogenetic Evolution | Phylogenetic analysis placed six 2023–2025 swine H1N1 isolates in the G4 genotype with EA-lineage HA/NA, pdm09-derived PB2/PB1/PA/NP/M, and a triple‑reassortant NS segment. | 42797971 |
| 2026-07-17 | Experimental Infection Pathogenicity Experiment | In human bronchial epithelial Calu-3 cells, H5N1 clade 2.3.4.4b viruses induced moderate type I interferon and proinflammatory responses, lower than A(H1N1)pdm09 and H5N1 clade 1. | 42466872 |
| 2026-07 | Functional Mechanism Molecular Adaptation | NS1-A53D enhances HA stability while maintaining receptor binding specificity, compensating for reduced receptor-binding affinity caused by HA mutations in H1N1 canine influenza virus. | 42176433 |
| 2026-07 | Functional Mechanism Molecular Adaptation | Adaptive mutations NS1-A53D and NEP-R42K synergistically enhance replication of H1N1 canine influenza virus by promoting vRNP nuclear export and increasing polymerase activity. | 42176433 |
| 2026-07 | Functional Mechanism Molecular Adaptation | Cooperative interactions among HA and NS gene mutations NS1-A53D and NEP-R42K drive mammalian adaptation and pathogenicity of H1N1 canine influenza virus through enhanced HA stability and vRNP export. | 42176433 |
| 2026-07 | Functional Mechanism Molecular Adaptation | Synergy between HA mutations N198D and A227E and NS1-A53D enhances early viral entry of H1N1 canine influenza virus through improved attachment and internalization. | 42176433 |
| 2026-07 | Experimental Infection Host Range Experiment | Wild bird surveillance isolates H5N3 and H7N1 showed minimal replication in human bronchial tissues compared with pandemic H1N1 and HPAI H5N1 in the ex vivo model. | 42397692 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
2 source articles
2 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-10 | Zoonotic Surveillance Virus Isolation | Fifty-six influenza A viruses were isolated from swine in Vietnam during 2020–2024, comprising 21 H1N1, 31 H1N2, and 4 H3N2 isolates. | 42811277 |
| 2026-09-29 | Genomic Evolution Phylogenetic Evolution | Phylogenetic analysis indicates that HA A227E and NA S369N substitutions were acquired in swine prior to the emergence of H1N1pdm09 in humans. | 42776754 |
| 2026-09-29 | Functional Mechanism Molecular Adaptation | In H1N1pdm09-related swine viruses, HA A227E reduces receptor binding and NA S369N in the 2SBS reduces NA cleavage, jointly adjusting the HA–NA balance linked to host-range adaptation before the 2009 pandemic emergence. | 42776754 |
No publication-dated literature was found for this virus in this window.
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
0 source articles
0 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| No publication-dated evidence in this window. | |||