Recent evidence findings
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
7 source articles
6 hosts
2 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-07-17 | Experimental Infection Pathogenicity Experiment | In human bronchial epithelial Calu-3 cells, H5N1 clade 2.3.4.4b viruses induced moderate type I interferon and proinflammatory responses, lower than A(H1N1)pdm09 and H5N1 clade 1. | 42466872 |
| 2026-07-11 | Zoonotic Surveillance Virus Isolation | Influenza A virus was successfully isolated 42 times from cloacal swabs of wild birds in the Lake Baikal basin, spanning 12 HA/NA subtype combinations. | 42515613 |
| 2026-07-02 | Experimental Infection Host Range Experiment | Mammalian-origin H1N1 strains replicated in bovine mammary gland organoids with efficiency comparable to bovine H5N1. | 42390302 |
| 2026-07 | Functional Mechanism Molecular Adaptation | NS1-A53D enhances HA stability while maintaining receptor binding specificity, compensating for reduced receptor-binding affinity caused by HA mutations in H1N1 canine influenza virus. | 42176433 |
| 2026-07 | Functional Mechanism Molecular Adaptation | Adaptive mutations NS1-A53D and NEP-R42K synergistically enhance replication of H1N1 canine influenza virus by promoting vRNP nuclear export and increasing polymerase activity. | 42176433 |
| 2026-07 | Functional Mechanism Molecular Adaptation | Cooperative interactions among HA and NS gene mutations NS1-A53D and NEP-R42K drive mammalian adaptation and pathogenicity of H1N1 canine influenza virus through enhanced HA stability and vRNP export. | 42176433 |
| 2026-07 | Functional Mechanism Molecular Adaptation | Synergy between HA mutations N198D and A227E and NS1-A53D enhances early viral entry of H1N1 canine influenza virus through improved attachment and internalization. | 42176433 |
| 2026-07 | Experimental Infection Host Range Experiment | Wild bird surveillance isolates H5N3 and H7N1 showed minimal replication in human bronchial tissues compared with pandemic H1N1 and HPAI H5N1 in the ex vivo model. | 42397692 |
| 2026-06 | Zoonotic Surveillance Serological Evidence | Influenza A(H1N1)pdm09 antibodies were detected in unvaccinated swine across Norwegian counties during 2009/2010–2022/2023, indicating serological exposure. | 41857313 |
| 2026-06 | Zoonotic Surveillance Serological Evidence | Temporal correlation of influenza A(H1N1)pdm09 antibody prevalence between humans and swine in Norway suggests possible bidirectional spillover at the swine–human interface. | 41857313 |
| 2026-05-25 | Genomic Evolution Recombination or Reassortment | Introductions of H1N1pdm09 from humans into pigs generated at least five reassortant influenza A virus genotypes in Spain that incorporated pandemic internal cassettes and, in some cases, human seasonal N2 segments. | 42244724 |
| 2026-05-25 | Transmission Evidence Spillover Event | Four human H1N1v infections detected in Spain between 2022 and 2026 were genomically linked to influenza A genotypes circulating in white pigs, indicating animal-to-human spillover. | 42244724 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
3 source articles
1 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-07-17 | Experimental Infection Pathogenicity Experiment | In human bronchial epithelial Calu-3 cells, H5N1 clade 2.3.4.4b viruses induced moderate type I interferon and proinflammatory responses, lower than A(H1N1)pdm09 and H5N1 clade 1. | 42466872 |
| 2026-07 | Functional Mechanism Molecular Adaptation | NS1-A53D enhances HA stability while maintaining receptor binding specificity, compensating for reduced receptor-binding affinity caused by HA mutations in H1N1 canine influenza virus. | 42176433 |
| 2026-07 | Functional Mechanism Molecular Adaptation | Adaptive mutations NS1-A53D and NEP-R42K synergistically enhance replication of H1N1 canine influenza virus by promoting vRNP nuclear export and increasing polymerase activity. | 42176433 |
| 2026-07 | Functional Mechanism Molecular Adaptation | Cooperative interactions among HA and NS gene mutations NS1-A53D and NEP-R42K drive mammalian adaptation and pathogenicity of H1N1 canine influenza virus through enhanced HA stability and vRNP export. | 42176433 |
| 2026-07 | Functional Mechanism Molecular Adaptation | Synergy between HA mutations N198D and A227E and NS1-A53D enhances early viral entry of H1N1 canine influenza virus through improved attachment and internalization. | 42176433 |
| 2026-07 | Experimental Infection Host Range Experiment | Wild bird surveillance isolates H5N3 and H7N1 showed minimal replication in human bronchial tissues compared with pandemic H1N1 and HPAI H5N1 in the ex vivo model. | 42397692 |
No publication-dated literature was found for this virus in this window.
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
0 source articles
0 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| No publication-dated evidence in this window. | |||