Virus entity

Influenza A virus H5N8

ScopeCurated virus entity IAV H5N8

Recent evidence findings

Evidence-grounded Research Brief · Past 3 months 8

Synthesizing linked evidence and source literature...

Generating an evidence-grounded brief with GPT-5...
2 source articles 2 hosts 1 countries
Publication date Category / type Key finding PMID
2026-08 Genomic Evolution Recombination or Reassortment H5N8 viruses from Egyptian waterfowl shifted from genotype G1 (2018 duck strains) to genotype G4 in 2022 due to segment reassortment across the 8 gene segments. 41498130
2026-08 Functional Mechanism Molecular Adaptation H5N8 strains from 2022 possessed internal gene markers associated with mammalian adaptation, including PB2 504V, PA 127V and 672L, and PB1 133G. 41498130
2026-08 Zoonotic Surveillance Viral Detection RT-qPCR detected H5N8 HPAI in 13 duck flocks and 11 geese flocks among 30 symptomatic waterfowl flocks; sampling was from Menoufia governorate, Egypt in 2022. 41498130
2026-08 Functional Mechanism Molecular Adaptation Brain-derived H5N8 isolates carried HA substitutions F244L, I248S, and K234R relative to tracheal isolates, suggesting adaptation linked to neurotropism. 41498130
2026-08 Genomic Evolution Phylogenetic Evolution HA phylogeny shows 2022 Egyptian H5N8 clade 2.3.4.4b isolates cluster with Russian and European-like strains, with mutations linked to antigenic drift and adaptation. 41498130
2026-08 Zoonotic Surveillance Virus Isolation H5N8 HPAI viruses were isolated from waterfowl in Egypt, yielding brain-derived and tracheal isolates. 41498130
2026-07-07 Genomic Evolution Phylogenetic Evolution Whole-genome phylogenetics assigned wild-bird H5 AIV isolates from East China to clades 2.3.2.1 and 2.3.4.4 across subtypes H5N1, H5N6, and H5N8. 42450817
2026-07-07 Zoonotic Surveillance Virus Isolation H5 avian influenza viruses (including H5N1, H5N6, and H5N8) were isolated from wild birds in East China during 2013–2022. 42450817
Evidence-grounded Research Brief · Past month 6

Synthesizing linked evidence and source literature...

Generating an evidence-grounded brief with GPT-5...
1 source articles 1 hosts 1 countries
Publication date Category / type Key finding PMID
2026-08 Genomic Evolution Recombination or Reassortment H5N8 viruses from Egyptian waterfowl shifted from genotype G1 (2018 duck strains) to genotype G4 in 2022 due to segment reassortment across the 8 gene segments. 41498130
2026-08 Functional Mechanism Molecular Adaptation H5N8 strains from 2022 possessed internal gene markers associated with mammalian adaptation, including PB2 504V, PA 127V and 672L, and PB1 133G. 41498130
2026-08 Zoonotic Surveillance Viral Detection RT-qPCR detected H5N8 HPAI in 13 duck flocks and 11 geese flocks among 30 symptomatic waterfowl flocks; sampling was from Menoufia governorate, Egypt in 2022. 41498130
2026-08 Functional Mechanism Molecular Adaptation Brain-derived H5N8 isolates carried HA substitutions F244L, I248S, and K234R relative to tracheal isolates, suggesting adaptation linked to neurotropism. 41498130
2026-08 Genomic Evolution Phylogenetic Evolution HA phylogeny shows 2022 Egyptian H5N8 clade 2.3.4.4b isolates cluster with Russian and European-like strains, with mutations linked to antigenic drift and adaptation. 41498130
2026-08 Zoonotic Surveillance Virus Isolation H5N8 HPAI viruses were isolated from waterfowl in Egypt, yielding brain-derived and tracheal isolates. 41498130
Evidence-grounded Research Brief · Past week 0

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Publication date Category / type Key finding PMID
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Evidence-related Animal

Evidence-related animal composition

14 animal taxa

Geographic evidence

Evidence distribution by country

9 countries

Temporal evidence

Evidence dynamics by year

38 year-type groups

Publication output

Source articles by month

143 months