Recent evidence findings
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
2 source articles
1 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-07-15 | Experimental Infection Host Range Experiment | PDCoV replicated efficiently without exogenous trypsin in human H1299 and Caco-2 cells and murine MC-38 cells, indicating high permissiveness. | 42515629 |
| 2026-07-15 | Experimental Infection Host Range Experiment | Human H1299 and Caco-2 and murine MC-38 cells were highly susceptible to PDCoV, whereas MCF-7, TE-10, and KYSE-410 were non-permissive. | 42515629 |
| 2026-07-15 | Experimental Infection Pathogenicity Experiment | High concentrations of trypsin triggered prominent syncytia formation in PDCoV-infected H1299, U251, and Neuro-2a cells. | 42515629 |
| 2026-07-15 | Experimental Infection Host Range Experiment | Exogenous trypsin enhanced PDCoV replication in semi-permissive cell lines in a concentration-dependent manner. | 42515629 |
| 2026-07-15 | Functional Mechanism Molecular Adaptation | Basal APN expression correlates with cellular susceptibility to PDCoV across tested cell lines. | 42515629 |
| 2026-07-02 | Functional Mechanism Receptor Usage | GRP78 binds the PDCoV S1 protein and promotes PDCoV attachment and internalization independent of pAPN. | 42390253 |
| 2026-07-02 | Functional Mechanism Receptor Usage | GRP78 binds the C-terminal domain of the PDCoV S1 protein via its substrate-binding domain. | 42390253 |
| 2026-07-02 | Functional Mechanism Receptor Usage | GRP78 facilitates PDCoV entry through clathrin-mediated endocytosis. | 42390253 |
| 2026-07-02 | Experimental Infection Host Range Experiment | Porcine deltacoronavirus (PDCoV) can infect pAPN-knockout cell lines and pigs, indicating susceptibility even without pAPN. | 42390253 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
1 source articles
0 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-07-15 | Experimental Infection Host Range Experiment | PDCoV replicated efficiently without exogenous trypsin in human H1299 and Caco-2 cells and murine MC-38 cells, indicating high permissiveness. | 42515629 |
| 2026-07-15 | Experimental Infection Host Range Experiment | Human H1299 and Caco-2 and murine MC-38 cells were highly susceptible to PDCoV, whereas MCF-7, TE-10, and KYSE-410 were non-permissive. | 42515629 |
| 2026-07-15 | Experimental Infection Pathogenicity Experiment | High concentrations of trypsin triggered prominent syncytia formation in PDCoV-infected H1299, U251, and Neuro-2a cells. | 42515629 |
| 2026-07-15 | Experimental Infection Host Range Experiment | Exogenous trypsin enhanced PDCoV replication in semi-permissive cell lines in a concentration-dependent manner. | 42515629 |
| 2026-07-15 | Functional Mechanism Molecular Adaptation | Basal APN expression correlates with cellular susceptibility to PDCoV across tested cell lines. | 42515629 |
No publication-dated literature was found for this virus in this window.
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
0 source articles
0 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| No publication-dated evidence in this window. | |||