Virus entity

SARS-related coronavirus

Levelvirus SARSr-CoV

Recent evidence findings

Research Brief · Past 3 months 9

Generating research brief from recent literature...

Summarizing recent literature with GPT-5...
3 literature 6 hosts 0 countries
Publication date Type Key finding PMID
2026-05-13 Molecular Adaptation A single amino acid difference in Orf9b between SARS-CoV-2 and RaTG13 acts as a molecular switch, redirecting binding between Tom70 and MTARC2, thereby modulating immune evasion and viral adaptation to human versus bat hosts. 42134328
2026-05-13 Molecular Adaptation A nonsynonymous mutation in the SARS-CoV-2 nucleocapsid protein enables replication in bat cells expressing human ACE2 and TMPRSS2, highlighting a molecular adaptation influencing cross-species infectivity. 42134328
2026-04-22 Molecular Adaptation Mutations F294L and A835D in the SHC014-CoV spike glycoprotein confer ACE2-dependent human cell infection, indicating molecular adaptation facilitating cross-species transmission. 42026866
2026-04-22 Receptor Usage SHC014-CoV uses human ACE2 for cell entry after acquiring F294L and A835D mutations in the spike ectodomain. 42026866
2026-04 Receptor Usage BANAL-236 spike-mediated entry into human and Rhinolophus cells requires human ACE2 and TMPRSS2 expression. 42008572
2026-04 Molecular Adaptation Multiple BANAL-236 proteins inhibit interferon production and signaling, showing molecular adaptation for innate immune evasion in human cells. 42008572
2026-04 Molecular Adaptation BANAL-236 spike protein mediates cell entry through human ACE2 and TMPRSS2, indicating receptor-binding adaptation that may facilitate human infection. 42008572
2026-04 Host Range Experiment BANAL-236 replicated in human cells expressing ACE2 and TMPRSS2, showing susceptibility of human cell systems to this bat sarbecovirus. 42008572
2026-04 Host Range Experiment BANAL-236 failed to replicate in wild-type Rhinolophus cells but replicated in Rhinolophus ferrumequinum cells engineered to express human ACE2 and TMPRSS2, indicating human receptor-dependent host range expansion. 42008572
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Evidence-related Animal

Evidence-related animal composition

29 animal taxa

Geographic evidence

Evidence distribution by country

4 countries

Temporal evidence

Evidence dynamics by year

77 year-type groups

Publication output

Literature publications by month

229 months