Recent evidence findings
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
2 source articles
3 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-08-10 | Functional Mechanism Molecular Adaptation | Deletion of 3'UTR SLI and/or SLIII in TMUV impairs replication in avian cells but not mammalian cells, and dual deletion reduces virulence in ducklings with limited impact in mice. | 42578371 |
| 2026-08-10 | Functional Mechanism Molecular Adaptation | TMUV 3'UTR SLI/SLIII promote replication in avian cells via interaction with the host factor CELF2. | 42578371 |
| 2026-08-10 | Functional Mechanism Molecular Adaptation | Duplication of SLII in the TMUV 3'UTR enhances replication in mammalian and avian cells but not mosquito cells, indicating host-specific proliferation effects. | 42578371 |
| 2026-08-10 | Functional Mechanism Molecular Adaptation | TMUV mutants retaining only one 3'UTR stem-loop are replication-attenuated, with efficiency dependent on which SL is retained. | 42578371 |
| 2026-07-29 | Experimental Infection Pathogenicity Experiment | Chicken-derived TMUV isolate WH2025 (cluster 3.2) caused 100% mortality in experimentally infected mice, indicating highest pathogenicity among tested isolates. | 42523112 |
| 2026-07-29 | Experimental Infection Host Range Experiment | Five TMUV isolates from clusters 2.1.1, 2.1.2, 2.2, 3.1, and 3.2 were experimentally tested in mice to assess mammalian pathogenicity; the chicken-derived cluster 3.2 isolate WH2025 caused 100% mortality. | 42523112 |
| 2026-07-29 | Experimental Infection Host Range Experiment | In Culex quinquefasciatus, contemporary duck-derived TMUV isolates from clusters 2 and 3.2 replicated and infected more efficiently than the ancestral mosquito-derived isolate MM 1775 (cluster 3.1). | 42523112 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
2 source articles
3 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-08-10 | Functional Mechanism Molecular Adaptation | Deletion of 3'UTR SLI and/or SLIII in TMUV impairs replication in avian cells but not mammalian cells, and dual deletion reduces virulence in ducklings with limited impact in mice. | 42578371 |
| 2026-08-10 | Functional Mechanism Molecular Adaptation | TMUV 3'UTR SLI/SLIII promote replication in avian cells via interaction with the host factor CELF2. | 42578371 |
| 2026-08-10 | Functional Mechanism Molecular Adaptation | Duplication of SLII in the TMUV 3'UTR enhances replication in mammalian and avian cells but not mosquito cells, indicating host-specific proliferation effects. | 42578371 |
| 2026-08-10 | Functional Mechanism Molecular Adaptation | TMUV mutants retaining only one 3'UTR stem-loop are replication-attenuated, with efficiency dependent on which SL is retained. | 42578371 |
| 2026-07-29 | Experimental Infection Pathogenicity Experiment | Chicken-derived TMUV isolate WH2025 (cluster 3.2) caused 100% mortality in experimentally infected mice, indicating highest pathogenicity among tested isolates. | 42523112 |
| 2026-07-29 | Experimental Infection Host Range Experiment | Five TMUV isolates from clusters 2.1.1, 2.1.2, 2.2, 3.1, and 3.2 were experimentally tested in mice to assess mammalian pathogenicity; the chicken-derived cluster 3.2 isolate WH2025 caused 100% mortality. | 42523112 |
| 2026-07-29 | Experimental Infection Host Range Experiment | In Culex quinquefasciatus, contemporary duck-derived TMUV isolates from clusters 2 and 3.2 replicated and infected more efficiently than the ancestral mosquito-derived isolate MM 1775 (cluster 3.1). | 42523112 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
1 source articles
0 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-08-10 | Functional Mechanism Molecular Adaptation | Deletion of 3'UTR SLI and/or SLIII in TMUV impairs replication in avian cells but not mammalian cells, and dual deletion reduces virulence in ducklings with limited impact in mice. | 42578371 |
| 2026-08-10 | Functional Mechanism Molecular Adaptation | TMUV 3'UTR SLI/SLIII promote replication in avian cells via interaction with the host factor CELF2. | 42578371 |
| 2026-08-10 | Functional Mechanism Molecular Adaptation | Duplication of SLII in the TMUV 3'UTR enhances replication in mammalian and avian cells but not mosquito cells, indicating host-specific proliferation effects. | 42578371 |
| 2026-08-10 | Functional Mechanism Molecular Adaptation | TMUV mutants retaining only one 3'UTR stem-loop are replication-attenuated, with efficiency dependent on which SL is retained. | 42578371 |