Recent evidence findings
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
1 source articles
1 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-07-17 | Functional Mechanism Molecular Adaptation | Host splicing factor domains U2AF1 RS and Zn1, and nearly all domains of U2AF2 except its RS domain, are required for proviral function during orthoflavivirus infection. | 42464737 |
| 2026-07-17 | Experimental Infection Host Range Experiment | Trans-complementation with the Aedes aegypti homolog u2af38 in U2AF1-knockout cells restores ZIKV replication, indicating cross-species functional support for infection. | 42464737 |
| 2026-07-17 | Functional Mechanism Molecular Adaptation | Host factors U2AF1 and U2AF2 bind viral RNA, with U2AF1 binding dependent on U2AF2, supporting a mechanistic role in viral protein synthesis/replication. | 42464737 |
| 2026-07-17 | Experimental Infection Host Range Experiment | Expressing Aedes aegypti u2af50 in U2AF2-knockdown cells did not restore ZIKV replication. | 42464737 |
| 2026-07-17 | Experimental Infection Host Range Experiment | U2AF2 and U2AF1 are critical host factors for efficient infection by Dengue virus and Zika virus at the viral protein synthesis stage in infected cells. | 42464737 |
| 2026-07-17 | Experimental Infection Host Range Experiment | Disrupting the U2AF1–U2AF2 interaction potently suppresses ZIKV infection in cells. | 42464737 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
1 source articles
1 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-07-17 | Functional Mechanism Molecular Adaptation | Host splicing factor domains U2AF1 RS and Zn1, and nearly all domains of U2AF2 except its RS domain, are required for proviral function during orthoflavivirus infection. | 42464737 |
| 2026-07-17 | Experimental Infection Host Range Experiment | Trans-complementation with the Aedes aegypti homolog u2af38 in U2AF1-knockout cells restores ZIKV replication, indicating cross-species functional support for infection. | 42464737 |
| 2026-07-17 | Functional Mechanism Molecular Adaptation | Host factors U2AF1 and U2AF2 bind viral RNA, with U2AF1 binding dependent on U2AF2, supporting a mechanistic role in viral protein synthesis/replication. | 42464737 |
| 2026-07-17 | Experimental Infection Host Range Experiment | Expressing Aedes aegypti u2af50 in U2AF2-knockdown cells did not restore ZIKV replication. | 42464737 |
| 2026-07-17 | Experimental Infection Host Range Experiment | U2AF2 and U2AF1 are critical host factors for efficient infection by Dengue virus and Zika virus at the viral protein synthesis stage in infected cells. | 42464737 |
| 2026-07-17 | Experimental Infection Host Range Experiment | Disrupting the U2AF1–U2AF2 interaction potently suppresses ZIKV infection in cells. | 42464737 |
No publication-dated literature was found for this virus in this window.
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
0 source articles
0 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| No publication-dated evidence in this window. | |||