Recent evidence findings
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
11 source articles
8 viruses
1 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-10-10 | Zoonotic Surveillance Viral Detection | RHEV RNA was detected in house mice (Mus musculus) in Northwestern Italy with a detection rate of 7.0% (6/86). | 42856010 |
| 2026-10-10 | Zoonotic Surveillance Viral Detection | RHEV-positive rodents were captured on five livestock farms across three municipalities in Northwestern Italy. | 42856010 |
| 2026-10-08 | Experimental Infection Pathogenicity Experiment | Two H9N2 viruses caused interstitial pneumonia and replicated in lungs and nasal turbinates of mice without significant weight loss or death and without detectable dissemination to other organs. | 42849636 |
| 2026-10 | Experimental Infection Host Range Experiment | In vivo challenge showed the H6N6 avian influenza virus infected mice, SPF chickens, and young Muscovy ducks, causing mild lesions. | 42385378 |
| 2026-09-29 | Experimental Infection Pathogenicity Experiment | H9N2 avian influenza viruses with combined N70S and Y155H neuraminidase mutations caused high pathogenicity in BALB/c mice without prior adaptation. | 42810520 |
| 2026-09-29 | Experimental Infection Pathogenicity Experiment | Neuraminidase inhibitors showed limited in vivo protective effect against H9N2 virus with combined N70S/Y155H mutations, potentially due to inability to ameliorate excessive inflammatory responses. | 42810520 |
| 2026-09-11 | Experimental Infection Host Range Experiment | After 13 serial passages in AG129 mice, a mouse-adapted HEV-C1 strain infected immunocompetent C57BL/6J mice. | 42727860 |
| 2026-09-11 | Zoonotic Surveillance Viral Detection | HEV RNA was detected in experimentally infected AG129 and C57BL/6J mice by RT-PCR and RNAscope. | 42727860 |
| 2026-09-11 | Experimental Infection Pathogenicity Experiment | Hepatitis E virus (HEV-C1) infection in AG129 and C57BL/6J mice was evaluated with liver function tests and histopathology to assess disease impact. | 42727860 |
| 2026-09-11 | Experimental Infection Pathogenicity Experiment | CD4+ T cell depletion in mice promoted establishment of persistent HEV-C1 infection, indicating immune-modulated chronicity. | 42727860 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | The PA/PA-X I94V mutation increases pathogenicity and viral fitness of H7N9 influenza A virus in mice. | 42090884 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | In a mouse model, the NelB strain of Nelson Bay orthoreovirus did not exhibit a virulent phenotype, in contrast to the virulent MB strain. | 42546031 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | Three poultry-derived H9N2 isolates replicated efficiently in mouse lungs without causing mortality, with CK/SD/TA1016/22 showing higher replication and more severe lung lesions. | 42184734 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | In PA-X–deficient H7N9 virus, adding the PA I94V mutation has no obvious effect on viral fitness in mice and chickens, implicating PA-X I94V in virulence modulation. | 42090884 |
| 2026-07-30 | Experimental Infection Pathogenicity Experiment | H9N2 replicated effectively in lungs and nasal turbinates of BALB/c mice without prior adaptation. | 42655013 |
| 2026-07-29 | Experimental Infection Pathogenicity Experiment | Chicken-derived TMUV isolate WH2025 (cluster 3.2) caused 100% mortality in experimentally infected mice, indicating highest pathogenicity among tested isolates. | 42523112 |
| 2026-07-29 | Experimental Infection Host Range Experiment | Five TMUV isolates from clusters 2.1.1, 2.1.2, 2.2, 3.1, and 3.2 were experimentally tested in mice to assess mammalian pathogenicity; the chicken-derived cluster 3.2 isolate WH2025 caused 100% mortality. | 42523112 |
| 2026-07-22 | Experimental Infection Pathogenicity Experiment | A representative H3N8 avian influenza virus infected BALB/c mice without prior adaptation, replicating mainly in the upper respiratory tract with limited extrapulmonary dissemination. | 42486182 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
4 source articles
4 viruses
1 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-10-10 | Zoonotic Surveillance Viral Detection | RHEV RNA was detected in house mice (Mus musculus) in Northwestern Italy with a detection rate of 7.0% (6/86). | 42856010 |
| 2026-10-10 | Zoonotic Surveillance Viral Detection | RHEV-positive rodents were captured on five livestock farms across three municipalities in Northwestern Italy. | 42856010 |
| 2026-10-08 | Experimental Infection Pathogenicity Experiment | Two H9N2 viruses caused interstitial pneumonia and replicated in lungs and nasal turbinates of mice without significant weight loss or death and without detectable dissemination to other organs. | 42849636 |
| 2026-10 | Experimental Infection Host Range Experiment | In vivo challenge showed the H6N6 avian influenza virus infected mice, SPF chickens, and young Muscovy ducks, causing mild lesions. | 42385378 |
| 2026-09-29 | Experimental Infection Pathogenicity Experiment | H9N2 avian influenza viruses with combined N70S and Y155H neuraminidase mutations caused high pathogenicity in BALB/c mice without prior adaptation. | 42810520 |
| 2026-09-29 | Experimental Infection Pathogenicity Experiment | Neuraminidase inhibitors showed limited in vivo protective effect against H9N2 virus with combined N70S/Y155H mutations, potentially due to inability to ameliorate excessive inflammatory responses. | 42810520 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
2 source articles
3 viruses
1 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-10-10 | Zoonotic Surveillance Viral Detection | RHEV RNA was detected in house mice (Mus musculus) in Northwestern Italy with a detection rate of 7.0% (6/86). | 42856010 |
| 2026-10-10 | Zoonotic Surveillance Viral Detection | RHEV-positive rodents were captured on five livestock farms across three municipalities in Northwestern Italy. | 42856010 |
| 2026-10-08 | Experimental Infection Pathogenicity Experiment | Two H9N2 viruses caused interstitial pneumonia and replicated in lungs and nasal turbinates of mice without significant weight loss or death and without detectable dissemination to other organs. | 42849636 |