Recent evidence findings
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
10 source articles
9 viruses
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-08 | Experimental Infection Pathogenicity Experiment | The PA/PA-X I94V mutation increases pathogenicity and viral fitness of H7N9 influenza A virus in mice. | 42090884 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | In a mouse model, the NelB strain of Nelson Bay orthoreovirus did not exhibit a virulent phenotype, in contrast to the virulent MB strain. | 42546031 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | Three poultry-derived H9N2 isolates replicated efficiently in mouse lungs without causing mortality, with CK/SD/TA1016/22 showing higher replication and more severe lung lesions. | 42184734 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | In PA-X–deficient H7N9 virus, adding the PA I94V mutation has no obvious effect on viral fitness in mice and chickens, implicating PA-X I94V in virulence modulation. | 42090884 |
| 2026-07-29 | Experimental Infection Pathogenicity Experiment | Chicken-derived TMUV isolate WH2025 (cluster 3.2) caused 100% mortality in experimentally infected mice, indicating highest pathogenicity among tested isolates. | 42523112 |
| 2026-07-29 | Experimental Infection Host Range Experiment | Five TMUV isolates from clusters 2.1.1, 2.1.2, 2.2, 3.1, and 3.2 were experimentally tested in mice to assess mammalian pathogenicity; the chicken-derived cluster 3.2 isolate WH2025 caused 100% mortality. | 42523112 |
| 2026-07-22 | Experimental Infection Pathogenicity Experiment | A representative H3N8 avian influenza virus infected BALB/c mice without prior adaptation, replicating mainly in the upper respiratory tract with limited extrapulmonary dissemination. | 42486182 |
| 2026-07-13 | Experimental Infection Pathogenicity Experiment | The H9N2 isolate HL55 infected BALB/c mice without prior adaptation, causing transient upper respiratory tract replication, ~9.2% weight loss, mild disease, and no mortality or systemic dissemination. | 42515623 |
| 2026-07-13 | Experimental Infection Host Range Experiment | H9N2 isolate HL55 directly infected BALB/c mice without prior adaptation, with transient upper respiratory tract replication and mild disease. | 42515623 |
| 2026-06-09 | Experimental Infection Pathogenicity Experiment | The rGETV-KO310 deletion mutant of Getah virus was profoundly attenuated in vivo, causing only transient morbidity and no mortality in neonatal and weaned mice. | 42262762 |
| 2026-06-03 | Experimental Infection Host Range Experiment | Mouse inoculation experiments demonstrated that the swine-origin A(H1N2) virus strain (A) caused marked clinical signs and mortality, while the turkey-adapted strain (B) and swine reference strain (C) produced weaker responses. | 42237404 |
| 2026-05 | Experimental Infection Pathogenicity Experiment | N57-based monoreassortant PRVs carrying the S1 or S2 segment of MB exhibited enhanced virulence and lower survival rates in mice compared with wild-type N57. | 42189872 |
| 2026-05 | Experimental Infection Pathogenicity Experiment | MB-based monoreassortant PRVs carrying the S1 or S2 genomic segment from N57 showed attenuated virulence with reduced lung viral loads and cytokine gene expression in mice. | 42189872 |
| 2026-05 | Experimental Infection Pathogenicity Experiment | PRV strain Nachunsulwe-57 (N57) exhibited low virulence compared with the human-derived strain Miyazaki-Bali/2007 (MB) in laboratory mice. | 42189872 |
| 2026-05 | Experimental Infection Pathogenicity Experiment | Group.y.2.3 H7N9 avian influenza virus isolates showed stronger replication and pathogenicity in mice, with isolate 782‑2 being the most virulent. | 41747464 |
| 2026-05 | Experimental Infection Host Range Experiment | A chicken-origin H7N9 isolate (229-4) infected mice experimentally, showing avian-to-mammalian cross-species transmission potential. | 41747464 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
5 source articles
5 viruses
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-08 | Experimental Infection Pathogenicity Experiment | The PA/PA-X I94V mutation increases pathogenicity and viral fitness of H7N9 influenza A virus in mice. | 42090884 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | In a mouse model, the NelB strain of Nelson Bay orthoreovirus did not exhibit a virulent phenotype, in contrast to the virulent MB strain. | 42546031 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | Three poultry-derived H9N2 isolates replicated efficiently in mouse lungs without causing mortality, with CK/SD/TA1016/22 showing higher replication and more severe lung lesions. | 42184734 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | In PA-X–deficient H7N9 virus, adding the PA I94V mutation has no obvious effect on viral fitness in mice and chickens, implicating PA-X I94V in virulence modulation. | 42090884 |
| 2026-07-29 | Experimental Infection Pathogenicity Experiment | Chicken-derived TMUV isolate WH2025 (cluster 3.2) caused 100% mortality in experimentally infected mice, indicating highest pathogenicity among tested isolates. | 42523112 |
| 2026-07-29 | Experimental Infection Host Range Experiment | Five TMUV isolates from clusters 2.1.1, 2.1.2, 2.2, 3.1, and 3.2 were experimentally tested in mice to assess mammalian pathogenicity; the chicken-derived cluster 3.2 isolate WH2025 caused 100% mortality. | 42523112 |
| 2026-07-22 | Experimental Infection Pathogenicity Experiment | A representative H3N8 avian influenza virus infected BALB/c mice without prior adaptation, replicating mainly in the upper respiratory tract with limited extrapulmonary dissemination. | 42486182 |
No publication-dated literature was found for this host in this window.
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
0 source articles
0 viruses
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| No publication-dated evidence in this window. | |||