Virus entity

Betacoronavirus

ScopeICTV Genus

Recent evidence findings

Evidence-grounded Research Brief · Past 3 months 43

Synthesizing linked evidence and source literature...

Generating an evidence-grounded brief with GPT-5...
17 source articles 23 hosts 7 countries
Publication date Category / type Key finding PMID
2026-07-29 Zoonotic Surveillance Viral Detection A MERS-related coronavirus (Betacoronavirus cameli) was detected by nested RT-PCR and HTS in a rectal swab from one Molossus molossus bat in southern Brazil (1/65, 1.5%). 42525174
2026-07-29 Genomic Evolution Phylogenetic Evolution Phylogenetic reconstruction of five genomic contigs placed the detected Betacoronavirus cameli within Merbecovirus and showed close relationship to MERS-CoV strains from bats and dromedary camels. 42525174
2026-07-21 Functional Mechanism Molecular Adaptation Several Guangdong pangolin coronaviruses carry a lysine substitution at spike residue 519 that confers marked immune evasion by modulating spike conformational state. 42267927
2026-07-21 Functional Mechanism Molecular Adaptation SARS-CoV-2 acquired a divergent immune-evasive mutation at spike residue 519. 42267927
2026-07-09 Genomic Evolution Phylogenetic Evolution Phylogenetic analysis of 293 SARS-CoV-2 genomes indicates repeated spillovers of human-adapted variants, including Omicron, into mink. 42425991
2026-07-09 Zoonotic Surveillance Viral Detection RT-PCR detected SARS-CoV-2 in nasal swabs from farmed mink in the United States with ~0.9% positivity (760/85,656) across 18 farms in six states during 2022-2023. 42425991
2026-07-09 Transmission Evidence Cross-species Transmission Mink-adapted SARS-CoV-2 Delta lineage AY.39 spread from a mink farm to neighboring free-ranging white-tailed deer. 42425991
2026-07-09 Transmission Evidence Outbreak Investigation Active surveillance in US farmed mink during 2022–2023 detected subclinical SARS-CoV-2 infections and interspecies transmission involving humans, mink, and wildlife. 42425991
2026-07-07 Zoonotic Surveillance Viral Detection A partial MERS-CoV genome (~20,180 bp; ~70% coverage) was detected in a Bar-headed goose in Tibet. 42372155
2026-07-07 Functional Mechanism Receptor Usage Tundra swan and Black swan ACE2 bind SARS-CoV-2 RBDs of Alpha, Beta, and Gamma variants but not the prototype virus. 42372155
2026-07-07 Experimental Infection Host Range Experiment HeLa cells expressing Tundra swan or Black swan ACE2 were transduced by pseudotyped SARS-CoV-2 Alpha, Beta, and Gamma variants but not by prototype SARS-CoV-2. 42372155
2026-07-07 Functional Mechanism Receptor Usage HeLa cells expressing Tundra swan or Black swan ACE2 are transduced by SARS-CoV-2 Alpha, Beta, and Gamma pseudoviruses but not prototype SARS-CoV-2. 42372155
2026-07-07 Zoonotic Surveillance Viral Detection Nearly full-length SARS-CoV-2 genomes were detected in Tundra swans in Jiangxi. 42372155
2026-07-07 Genomic Evolution Phylogenetic Evolution The SARS-CoV-2 genome IMCAS_M2 from a Tundra swan possesses the Gamma VOC-characteristic RBD mutations K417T, E484K, and N501Y. 42372155
2026-07-07 Genomic Evolution Phylogenetic Evolution SARS-CoV-2 genomes IMCAS_M1 and IMCAS_M3 from Tundra swans carry the Beta VOC-characteristic RBD mutations K417N, E484K, and N501Y. 42372155
2026-07-07 Functional Mechanism Receptor Usage Cryo-EM structures show polar contacts and hydrophobic interactions mediating engagement between swan ACE2 and SARS-CoV-2 RBD. 42372155
2026-07-03 Zoonotic Surveillance Serological Evidence In the same cat population, 3.1% were seropositive for SARS-CoV-2 antibodies confirmed by neutralization. 42427631
2026-07-03 Zoonotic Surveillance Reservoir Ecology Owned and feral cats in the Philadelphia area show minimal evidence of routine exposure to clade 2.3.4.4b H5N1 but more common exposure to SARS-CoV-2. 42427631
2026-07-02 Zoonotic Surveillance Serological Evidence Pre-existing SARS-CoV-2 immune memory showed reduced cross-neutralizing activity against the bat sarbecovirus PRD0038. 42427868
2026-07 Experimental Infection Host Range Experiment Seasonal influenza A H1N1, H3N2, influenza B, MERS-CoV, and SARS-CoV productively replicated and infected human bronchial tissues in an ex vivo model. 42397692
2026-07-01 Zoonotic Surveillance Serological Evidence SARS-CoV-2 antibodies were detected in an Asian golden cat (Catopuma temminckii) from a German zoo cohort using sVNT and RBD-based ELISA. 42387664
2026-07-01 Zoonotic Surveillance Serological Evidence SARS-CoV-2 antibodies were detected in a European moose (Alces alces) from a German zoo cohort using sVNT and RBD-based ELISA. 42387664
2026-07 Experimental Infection Pathogenicity Experiment In an in vitro human alveolar model, HPAI H5N1, H7N9, MERS-CoV, and SARS-CoV caused more severe impairment of alveolar fluid clearance than seasonal H1N1, H3N2, and influenza B viruses. 42397692
2026-06-30 Zoonotic Surveillance Viral Detection One animal handler in Ghana tested positive for SARS-CoV-2. 42515577
2026-06-25 Zoonotic Surveillance Viral Detection Two clades of SARS-CoV-2-related coronaviruses were detected co-circulating in a horseshoe bat population in Thailand. 42097139
2026-06-25 Genomic Evolution Phylogenetic Evolution Phylogeographic analysis indicates SARS-CoV-2-related coronaviruses in Southeast Asia have a complex evolutionary history with extensive, recent geographic movement. 42097139
2026-06-25 Genomic Evolution Recombination or Reassortment SARS-CoV-2-related coronaviruses from Thailand show recombination with co-circulating virus lineages. 42097139
2026-06-25 Experimental Infection Host Range Experiment One clade of newly identified SARS-CoV-2-related coronaviruses from Thai horseshoe bats can use human ACE2 but shows reduced fusogenicity and replication in vitro compared with SARS-CoV-2. 42097139
2026-06-25 Experimental Infection Pathogenicity Experiment In hamster experiments, one newly identified SC2r-CoV clade showed lower pathogenicity than SARS-CoV-2. 42097139
2026-06-24 Experimental Infection Host Range Experiment JN.1 descendant SARS-CoV-2 variants infected cells expressing ACE2 orthologs from diverse mammalian species in a VSV pseudovirus system. 42400485
2026-06-24 Zoonotic Surveillance Serological Evidence Serum neutralization assays showed that LP.8.1.1, KP.3, XEC.25.1, XFG, and NB.1.8.1 had enhanced immune evasion compared with the JN.1 strain. 42400485
2026-06-17 Functional Mechanism Receptor Usage SARS-CoV-2 virus-like particles show a distinct preference for BSG-dependent cellular entry compared to DPP4-mediated entry. 42300082
2026-06 Zoonotic Surveillance Viral Detection Betacoronavirus erinacei RNA was detected by pan-CoV nested RT-PCR in fecal samples from pet long-eared hedgehogs (Hemiechinus auritus) in Italy. 42111335
2026-06 Genomic Evolution Phylogenetic Evolution Phylogenetic analysis showed that the Betacoronavirus erinacei strain detected in pet hedgehogs formed a distinct clade within European sequences, clustering with viruses from Europe and Eastern Russia rather than those from China in Amur hedgehogs. 42111335
2026-06 Zoonotic Surveillance Viral Detection SARS-CoV-2 nucleic acid was tested for and not detected in retropharyngeal lymph nodes from 110 Swedish roe deer. 41783616
2026-06 Zoonotic Surveillance Reservoir Ecology A long‑eared hedgehog‑specific strain of Betacoronavirus erinacei was identified, supporting circulation of related coronaviruses among hedgehog species across Europe and Eurasia. 42111335
2026-06 Zoonotic Surveillance Viral Detection Farm air samples were valuable for detecting respiratory bovine coronavirus. 41695450
2026-06 Zoonotic Surveillance Viral Detection Bovine coronavirus was more frequently detected in slurry and wastewater samples during winter. 41695450
2026-05-26 Experimental Infection Pathogenicity Experiment MERS-CoV infection caused lethal disease in transgenic hDPP4 Syrian hamsters. 42244650
2026-05-20 Zoonotic Surveillance Viral Detection Detection of Betacoronavirus erinacei sequences in non-hedgehog wild mammals indicates probable cross-species transmission among wildlife in Northern Italy. 42163369
2026-05-20 Zoonotic Surveillance Serological Evidence Anti-SARS-CoV-2 antibodies were detected in multiple wild mammal species from the Emilia-Romagna region of Italy. 42163369
2026-05-20 Zoonotic Surveillance Viral Detection EmbeCoV-related viral RNA sequences were detected in a porcupine in Emilia-Romagna, Italy. 42163369
2026-05-20 Zoonotic Surveillance Viral Detection Betacoronavirus erinacei RNA was detected in fox, porcupine, hare, and roe deer in Emilia-Romagna, Italy. 42163369
Evidence-grounded Research Brief · Past month 6

Synthesizing linked evidence and source literature...

Generating an evidence-grounded brief with GPT-5...
3 source articles 3 hosts 1 countries
Publication date Category / type Key finding PMID
2026-07-29 Zoonotic Surveillance Viral Detection A MERS-related coronavirus (Betacoronavirus cameli) was detected by nested RT-PCR and HTS in a rectal swab from one Molossus molossus bat in southern Brazil (1/65, 1.5%). 42525174
2026-07-29 Genomic Evolution Phylogenetic Evolution Phylogenetic reconstruction of five genomic contigs placed the detected Betacoronavirus cameli within Merbecovirus and showed close relationship to MERS-CoV strains from bats and dromedary camels. 42525174
2026-07-21 Functional Mechanism Molecular Adaptation Several Guangdong pangolin coronaviruses carry a lysine substitution at spike residue 519 that confers marked immune evasion by modulating spike conformational state. 42267927
2026-07-21 Functional Mechanism Molecular Adaptation SARS-CoV-2 acquired a divergent immune-evasive mutation at spike residue 519. 42267927
2026-07 Experimental Infection Host Range Experiment Seasonal influenza A H1N1, H3N2, influenza B, MERS-CoV, and SARS-CoV productively replicated and infected human bronchial tissues in an ex vivo model. 42397692
2026-07 Experimental Infection Pathogenicity Experiment In an in vitro human alveolar model, HPAI H5N1, H7N9, MERS-CoV, and SARS-CoV caused more severe impairment of alveolar fluid clearance than seasonal H1N1, H3N2, and influenza B viruses. 42397692
Evidence-grounded Research Brief · Past week 0

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0 source articles 0 hosts 0 countries
Publication date Category / type Key finding PMID
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Evidence-related Animal

Evidence-related animal composition

230 animal taxa

Geographic evidence

Evidence distribution by country

58 countries

Temporal evidence

Evidence dynamics by year

184 year-type groups

Publication output

Source articles by month

284 months