Virus entity

Influenza A virus H5N6

Levelsubtype IAV H5N6

Recent evidence findings

Research Brief · Past 3 months 8

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1 literature 4 hosts 1 countries
Publication date Type Key finding PMID
2026-04-06 Molecular Adaptation The duck-origin H5N6 virus exhibited hemagglutinin, neuraminidase, and polymerase mutations corresponding to partial adaptation to mammalian hosts through enhanced receptor binding, drug resistance, and improved replication efficiency. 41946007
2026-04-06 Host Range Experiment Duck-origin H5N6 virus transmitted among guinea pigs via both direct contact and airborne routes, demonstrating mammalian transmissibility. 41946007
2026-04-06 Host Range Experiment Duck-origin H5N6 virus caused moderate disease and lung pathology in experimentally infected mice. 41946007
2026-04-06 Host Range Experiment Duck-origin H5N6 virus showed increased replication in mammalian cells and was transmissible by contact and airborne routes in guinea pigs, indicating cross-species host adaptation. 41946007
2026-04-06 Cross Species Transmission A duck-origin clade 2.3.4.4b H5N6 avian influenza virus was able to transmit by direct contact and airborne routes among guinea pigs, showing animal-to-animal cross-species transmissibility. 41946007
2026-04-06 Zoonotic Surveillance A duck-origin H5N6 avian influenza virus was detected in Jiangsu, China via routine surveillance among ducks, reflecting active monitoring for zoonotic influenza circulation. 41946007
2026-04-06 Genomic Evolution Phylogenetic and molecular analysis showed that the duck-origin H5N6 virus was closely related to a human H5N6 strain and contained multiple mutations associated with mammalian adaptation. 41946007
2026-04-06 Receptor Usage The duck-origin H5N6 virus contains HA mutations that enhance human receptor binding and demonstrate dual receptor-binding specificity consistent with partial mammalian receptor adaptation. 41946007
Research Brief · Past month 0

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Evidence-related Animal

Evidence-related animal composition

7 animal taxa

Geographic evidence

Evidence distribution by country

1 countries

Temporal evidence

Evidence dynamics by year

35 year-type groups

Publication output

Literature publications by month

118 months