Recent evidence findings
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
2 source articles
3 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-08 | Functional Mechanism Molecular Adaptation | In H7N9 virus, the PA-X I94V mutation enhances viral polymerase activity and replication in mammalian cells. | 42090884 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | The PA/PA-X I94V mutation increases pathogenicity and viral fitness of H7N9 influenza A virus in mice. | 42090884 |
| 2026-08 | Genomic Evolution Phylogenetic Evolution | Recent sequence analysis shows high variation at PA/PA-X site 94 in H5N1 and H7N9, with the PA-X I94V mutation becoming prevalent in recent human H7N9 viruses. | 42090884 |
| 2026-08 | Functional Mechanism Molecular Adaptation | The PA-X I94V mutation in H7N9 modulates PA-X–mediated host shutoff, inhibiting antiviral and cell death–related responses. | 42090884 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | The PA/PA-X I94V mutation attenuates virulence of H7N9 influenza A virus in chickens. | 42090884 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | In PA-X–deficient H7N9 virus, adding the PA I94V mutation has no obvious effect on viral fitness in mice and chickens, implicating PA-X I94V in virulence modulation. | 42090884 |
| 2026-07 | Experimental Infection Pathogenicity Experiment | In an in vitro human alveolar model, HPAI H5N1, H7N9, MERS-CoV, and SARS-CoV caused more severe impairment of alveolar fluid clearance than seasonal H1N1, H3N2, and influenza B viruses. | 42397692 |
No publication-dated literature was found for this virus in this window.
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
0 source articles
0 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| No publication-dated evidence in this window. | |||
No publication-dated literature was found for this virus in this window.
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
0 source articles
0 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| No publication-dated evidence in this window. | |||