Recent evidence findings
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
8 source articles
5 hosts
2 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-08-07 | Genomic Evolution Phylogenetic Evolution | HA phylogeny assigns the 2023 Pakistani H9N2 isolates to the G5.3.2 (formerly B2) sub-lineage within the G1 Eurasian lineage. | 42566313 |
| 2026-08-07 | Zoonotic Surveillance Virus Isolation | Five H9N2 avian influenza virus isolates were obtained from poultry in Pakistan between January and March 2023. | 42566313 |
| 2026-08-07 | Genomic Evolution Phylogenetic Evolution | All eight gene segments of the 2023 Pakistani H9N2 isolates are closely related to prior Pakistani strains with no recent reassortment, consistent with localized persistence and drift. | 42566313 |
| 2026-08-07 | Functional Mechanism Receptor Usage | G1-lineage H9N2 isolates from Pakistan bind both α2,3- and α2,6-linked sialic acid receptors, with stronger affinity for α2,6. | 42566313 |
| 2026-08-07 | Functional Mechanism Molecular Adaptation | H9N2 isolates carried several mammalian-adaptive mutations in internal genes, indicating potential cross-species transmission risk. | 42566313 |
| 2026-08 | Genomic Evolution Recombination or Reassortment | Shandong poultry H9N2 isolates are reassortants combining G1-like (PB2, M), SH/F98-like (PB1, PA, NP, NS), and Y280-like (HA, NA) lineage segments. | 42184734 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | Three poultry-derived H9N2 isolates replicated efficiently in mouse lungs without causing mortality, with CK/SD/TA1016/22 showing higher replication and more severe lung lesions. | 42184734 |
| 2026-08 | Functional Mechanism Molecular Adaptation | H9N2 isolates carried human-adapted HA receptor-binding mutations and mammalian-adaptation mutations in polymerase and other genes, indicating enhanced mammalian adaptation potential. | 42184734 |
| 2026-08 | Zoonotic Surveillance Virus Isolation | Eight H9N2 avian influenza virus strains were successfully isolated from RT‑qPCR–positive chicken samples in Shandong Province, China. | 42184734 |
| 2026-08 | Zoonotic Surveillance Viral Detection | RT-qPCR detected H9N2 avian influenza virus in diseased chickens in Shandong Province during 2021–2023, with 10 positives out of 192 samples. | 42184734 |
| 2026-08 | Genomic Evolution Phylogenetic Evolution | Phylogenetic analysis of poultry-derived H9N2 isolates from Shandong showed a multi-lineage genome composition with PB2 and M from G1-like, PB1/PA/NP/NS from SH/F98-like, and HA/NA from Y280-like lineages, indicating reassortment. | 42184734 |
| 2026-07-22 | Genomic Evolution Recombination or Reassortment | H3N3 isolates were reassortants with HA from the novel H3N8 AIV lineage, NA from H10N3 AIV, and internal genes from H9N2 AIV. | 42486182 |
| 2026-07-22 | Genomic Evolution Recombination or Reassortment | An H3N8 isolate was a triple-reassortant with Eurasian avian H3, North American avian N8, and H9N2-derived internal genes. | 42486182 |
| 2026-07-13 | Experimental Infection Pathogenicity Experiment | The H9N2 isolate HL55 infected BALB/c mice without prior adaptation, causing transient upper respiratory tract replication, ~9.2% weight loss, mild disease, and no mortality or systemic dissemination. | 42515623 |
| 2026-07-13 | Experimental Infection Host Range Experiment | H9N2 isolate HL55 directly infected BALB/c mice without prior adaptation, with transient upper respiratory tract replication and mild disease. | 42515623 |
| 2026-07-13 | Genomic Evolution Recombination or Reassortment | H9N2 isolates possess a reassortant mosaic genome with HA from BJ/94-like, PB1/NP/NS from F98-like, NA from FJ/30-C-like, and PB2/M from G1-like lineages. | 42515623 |
| 2026-07-13 | Functional Mechanism Receptor Usage | H9N2 isolates HL55 and HL56 bind both avian α2-3 and human α2-6 sialic acid receptors, whereas HL45 binds only avian α2-3. | 42515623 |
| 2026-07-13 | Zoonotic Surveillance Virus Isolation | Three H9N2 avian influenza virus isolates were recovered from apparently healthy poultry in a Changchun live poultry market in 2022. | 42515623 |
| 2026-07-13 | Functional Mechanism Molecular Adaptation | H9N2 isolates carry mammalian-adaptation markers PB2 A588V, NA stalk deletion, and HA position 226 leucine, features linked to enhanced zoonotic adaptation including receptor binding and mammalian infectivity. | 42515623 |
| 2026-07-13 | Genomic Evolution Phylogenetic Evolution | Bayesian molecular clock analysis dated the H9N2 isolates’ MRCA to February 2022, with HL55 and HL56 diverging by May 2022, indicating rapid local evolution. | 42515623 |
| 2026-07-02 | Experimental Infection Host Range Experiment | Low pathogenic avian H9N2 exhibited restricted replication in bovine mammary gland organoids. | 42390302 |
| 2026-07 | Experimental Infection Host Range Experiment | H5N6 and H9N2 displayed differential lung replication and tissue tropism in human respiratory explants. | 42397692 |
| 2026-06-30 | Zoonotic Surveillance Viral Detection | Influenza A(H9N2) was detected exclusively in poultry in Ghana with a prevalence of 5.67%. | 42515577 |
| 2026-06-30 | Genomic Evolution Phylogenetic Evolution | Whole-genome phylogenetic analysis placed Ghanaian A(H9N2) strains in clade G1. | 42515577 |
| 2026-06-30 | Zoonotic Surveillance Viral Detection | Live bird markets in Ghana had significantly higher odds of A(H9N2) detection than commercial farms, while backyard farms had lower odds. | 42515577 |
| 2026-06-30 | Functional Mechanism Molecular Adaptation | Ghanaian A(H9N2) strains belonged to clade G1 and carried mammalian-adaptive markers. | 42515577 |
| 2026-06-30 | Zoonotic Surveillance Viral Detection | The Northern belt of Ghana recorded the highest prevalence of A(H9N2) detections in poultry. | 42515577 |
| 2026-06-30 | Zoonotic Surveillance Viral Detection | Environmental samples in Ghana tested negative for A(H9N2). | 42515577 |
| 2026-06 | Genomic Evolution Recombination or Reassortment | The duck-origin H6N2 GXG strain was identified as a triple-reassortant avian influenza virus containing a matrix gene derived from an H9N2 lineage. | 41931194 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
4 source articles
4 hosts
1 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-08-07 | Genomic Evolution Phylogenetic Evolution | HA phylogeny assigns the 2023 Pakistani H9N2 isolates to the G5.3.2 (formerly B2) sub-lineage within the G1 Eurasian lineage. | 42566313 |
| 2026-08-07 | Zoonotic Surveillance Virus Isolation | Five H9N2 avian influenza virus isolates were obtained from poultry in Pakistan between January and March 2023. | 42566313 |
| 2026-08-07 | Genomic Evolution Phylogenetic Evolution | All eight gene segments of the 2023 Pakistani H9N2 isolates are closely related to prior Pakistani strains with no recent reassortment, consistent with localized persistence and drift. | 42566313 |
| 2026-08-07 | Functional Mechanism Receptor Usage | G1-lineage H9N2 isolates from Pakistan bind both α2,3- and α2,6-linked sialic acid receptors, with stronger affinity for α2,6. | 42566313 |
| 2026-08-07 | Functional Mechanism Molecular Adaptation | H9N2 isolates carried several mammalian-adaptive mutations in internal genes, indicating potential cross-species transmission risk. | 42566313 |
| 2026-08 | Genomic Evolution Recombination or Reassortment | Shandong poultry H9N2 isolates are reassortants combining G1-like (PB2, M), SH/F98-like (PB1, PA, NP, NS), and Y280-like (HA, NA) lineage segments. | 42184734 |
| 2026-08 | Experimental Infection Pathogenicity Experiment | Three poultry-derived H9N2 isolates replicated efficiently in mouse lungs without causing mortality, with CK/SD/TA1016/22 showing higher replication and more severe lung lesions. | 42184734 |
| 2026-08 | Functional Mechanism Molecular Adaptation | H9N2 isolates carried human-adapted HA receptor-binding mutations and mammalian-adaptation mutations in polymerase and other genes, indicating enhanced mammalian adaptation potential. | 42184734 |
| 2026-08 | Zoonotic Surveillance Virus Isolation | Eight H9N2 avian influenza virus strains were successfully isolated from RT‑qPCR–positive chicken samples in Shandong Province, China. | 42184734 |
| 2026-08 | Zoonotic Surveillance Viral Detection | RT-qPCR detected H9N2 avian influenza virus in diseased chickens in Shandong Province during 2021–2023, with 10 positives out of 192 samples. | 42184734 |
| 2026-08 | Genomic Evolution Phylogenetic Evolution | Phylogenetic analysis of poultry-derived H9N2 isolates from Shandong showed a multi-lineage genome composition with PB2 and M from G1-like, PB1/PA/NP/NS from SH/F98-like, and HA/NA from Y280-like lineages, indicating reassortment. | 42184734 |
| 2026-07-22 | Genomic Evolution Recombination or Reassortment | H3N3 isolates were reassortants with HA from the novel H3N8 AIV lineage, NA from H10N3 AIV, and internal genes from H9N2 AIV. | 42486182 |
| 2026-07-22 | Genomic Evolution Recombination or Reassortment | An H3N8 isolate was a triple-reassortant with Eurasian avian H3, North American avian N8, and H9N2-derived internal genes. | 42486182 |
| 2026-07 | Experimental Infection Host Range Experiment | H5N6 and H9N2 displayed differential lung replication and tissue tropism in human respiratory explants. | 42397692 |
Synthesizing linked evidence and source literature...
Generating an evidence-grounded brief with GPT-5... AI-assisted synthesis grounded in linked OVE records and source literature. Verify details against the cited evidence.
1 source articles
1 hosts
0 countries
| Publication date | Category / type | Key finding | PMID |
|---|---|---|---|
| 2026-08-07 | Genomic Evolution Phylogenetic Evolution | HA phylogeny assigns the 2023 Pakistani H9N2 isolates to the G5.3.2 (formerly B2) sub-lineage within the G1 Eurasian lineage. | 42566313 |
| 2026-08-07 | Zoonotic Surveillance Virus Isolation | Five H9N2 avian influenza virus isolates were obtained from poultry in Pakistan between January and March 2023. | 42566313 |
| 2026-08-07 | Genomic Evolution Phylogenetic Evolution | All eight gene segments of the 2023 Pakistani H9N2 isolates are closely related to prior Pakistani strains with no recent reassortment, consistent with localized persistence and drift. | 42566313 |
| 2026-08-07 | Functional Mechanism Receptor Usage | G1-lineage H9N2 isolates from Pakistan bind both α2,3- and α2,6-linked sialic acid receptors, with stronger affinity for α2,6. | 42566313 |
| 2026-08-07 | Functional Mechanism Molecular Adaptation | H9N2 isolates carried several mammalian-adaptive mutations in internal genes, indicating potential cross-species transmission risk. | 42566313 |