Avian Influenza A(H7N2) Virus in Human Exposed to Sick Cats, New York, USA, 2016.

Atanaska Marinova-Petkova Jen Laplante Yunho Jang Brian Lynch Natosha Zanders Marisela Rodriguez Joyce Jones Sharmi Thor Erin Hodges Juan A De La Cruz Jessica Belser Hua Yang Paul Carney Bo Shu LaShondra Berman Thomas Stark John Barnes Fiona Havers Patrick Yang Susan C Trock Alicia Fry Larisa Gubareva Joseph S Bresee James Stevens Demetre Daskalakis Dakai Liu Christopher T Lee Mia Kim Torchetti Sandra Newbury Francine Cigel Kathy Toohey-Kurth Kirsten St George David E Wentworth Stephen Lindstrom C Todd Davis

PMID29148400 DOI10.3201/eid2312.170798 Year2017 Journal Emerging infectious diseases Emerg Infect Dis Languageeng Statusppublish

Abstract

An outbreak of influenza A(H7N2) virus in cats in a shelter in New York, NY, USA, resulted in zoonotic transmission. Virus isolated from the infected human was closely related to virus isolated from a cat; both were related to low pathogenicity avian influenza A(H7N2) viruses detected in the United States during the early 2000s.

Supporting text Virus Host Location

A(H7N2) 1 animal shelter 1 Avian influenza 57 cat-to-human transmission 1 H7N2 1 human infection with H7N2 1 influenza 61 interspecies transmission 51 New York 3 respiratory infections 30 United States 56 viruses 117 Disease Outbreaks 170 Genome, Viral 317 Animals 1948 Antigens, Viral 49 Binding Sites 89 Birds 212 Cat Diseases 67 Cats 120 Hemagglutinin Glycoproteins, Influenza Virus 180 Housing, Animal 5 Humans 1440 Influenza A Virus, H7N2 Subtype 3

Evidence records

5 total

Zoonotic Surveillance

2 records · 1 evidence types

Evidence type Virus Isolation

2 records

OVE2766 Virus Isolation

Key finding

Influenza A(H7N2) virus was successfully isolated from the infected human case.

Virus

Host

Location

Supporting text

Virus isolated from the infected human was closely related to virus isolated from a cat;

OVE2767 Virus Isolation

Key finding

Influenza A(H7N2) virus was successfully isolated from an infected cat in New York, USA.

Virus

Host

Location

Supporting text

Virus isolated from the infected human was closely related to virus isolated from a cat;

Transmission Evidence

2 records · 2 evidence types

Evidence type Spillover Event

1 records

OVE2765 Spillover Event

Key finding

Influenza A(H7N2) virus was transmitted from cats to a human exposed in a New York animal shelter outbreak.

Virus

Host

Location

Supporting text

An outbreak of influenza A(H7N2) virus in cats in a shelter in New York, NY, USA, resulted in zoonotic transmission.

Method: virus isolation | genomic comparison
Study design: outbreak investigation with human infection confirmation
Transmission direction: animal-to-human
Geographic raw: New York, NY, USA
Country inferred: USA

Evidence type Outbreak Investigation

1 records

OVE2764 Outbreak Investigation

Key finding

An outbreak of influenza A(H7N2) virus occurred among cats in a shelter in New York, USA, and was investigated for zoonotic transmission to a human.

Virus

Host

Location

Supporting text

An outbreak of influenza A(H7N2) virus in cats in a shelter in New York, NY, USA, resulted in zoonotic transmission.

Method: outbreak investigation | virus isolation | epidemiologic analysis
Transmission direction: animal-to-human
Geographic raw: New York, NY, USA
Country inferred: USA
Outbreak setting: animal shelter
Outbreak time: 2016
Outbreak scale: outbreak among cats with one human infection

Genomic Evolution

1 records · 1 evidence types

Evidence type Phylogenetic Evolution

1 records

OVE2768 Phylogenetic Evolution

Key finding

Phylogenetic analysis showed that influenza A(H7N2) viruses isolated from the infected human and from a cat were closely related to each other and to low pathogenicity avian influenza A(H7N2) viruses previously detected in the United States.

Virus

Host

Location

Supporting text

Virus isolated from the infected human was closely related to virus isolated from a cat; both were related to low pathogenicity avian influenza A(H7N2) viruses detected in the United States during the early 2000s.

Analysis methods: phylogenetic analysis

References

15 references

Reference network

Force-directed citation graph. OmniVira-indexed references are prioritized and recursively expanded up to three steps.

260 nodes · 391 links · capped

Drag nodes to explore citation neighborhoods


PMID 19523282	Past, present, and possible future human infection with influenza virus A subtype H7	Belser	2009
-	Influenza at the human-animal interface	World Health Organization	2017
-	Live-bird markets in the northeastern United States: a source of avian influenza in commercial poultry. In: Schrijver RS and Koch G, editors. Proceedings of the Frontis Workshop on Avian Influenza: Prevention and Control. Wageningen (the Netherlands): Springer; 2003. p. 19–24	Senne	2003
-	An overview of the 2002 outbreak of low-pathogenic H7N2 avian influenza in Virginia, West Virginia and North Carolina. In: Schrijver RS and Koch G, editors. Proceedings of the Frontis Workshop on Avian Influenza: Prevention and Control. Wageningen (the Netherlands): Springer; 2003. p. 41–7	Senne	2003
PMID 15071427	Update: influenza activity—United States, 2003-04 season	Centers for Disease Control and Preventi	2004
PMID 22710273	Low pathogenic avian influenza A (H7N2) virus infection in immunocompromised adult, New York, USA, 2003	Ostrowsky	2012
PMID 17913860	Development and evaluation of an Influenza virus subtype H7N2 vaccine candidate for pandemic preparedness	Pappas	2007
PMID 20824086 In OmniVira	Structures of receptor complexes of a North American H7N2 influenza hemagglutinin with a loop deletion in the receptor binding site.	Yang	2010
PMID 18508975 In OmniVira	Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility.	Belser	2008
PMID 24027325 In OmniVira	Structural analysis of the hemagglutinin from the recent 2013 H7N9 influenza virus.	Yang	2013
PMID 7142180	Sialylation of glycoprotein oligosaccharides N -linked to asparagine. Enzymatic characterization of a Gal β 1 to 3(4)GlcNAc α 2 to 3 sialyltransferase and a Gal β 1 to 4GlcNAc α 2 to 6 sialyltransferase from rat liver	Weinstein	1982
PMID 14745020	Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome	Fouchier	2004
PMID 17690300 In OmniVira	Immunization by avian H5 influenza hemagglutinin mutants with altered receptor binding specificity.	Yang	2007
PMID 9882316 In OmniVira	The surface glycoproteins of H5 influenza viruses isolated from humans, chickens, and wild aquatic birds have distinguishable properties.	Matrosovich	1999
-	Overview of avian influenza surveillance in the United States. US Department of Agriculture, Animal and Plant Health Inspection Service. 2015. [cited 2017 Feb 12]	Myers	2017