OmniVira

No Evidence of SARS-CoV-2 Infection in Neotropical Primates Sampled During COVID-19 Pandemic in Minas Gerais and Rio Grande do Sul, Brazil.

Filipe Vieira Santos de Abreu1 Mariana Viana Macedo2 Alex Junio Jardim da Silva1 Cirilo Henrique de Oliveira1 Vinícius Oliveira de Ottone2 Marco Antônio Barreto de Almeida3 Edmilson Dos Santos3 Jader Cruz da Cardoso3 Aline Scarpellini Campos3 Claudia Maria Dornelles da Silva3 Amanda Gonzales da Silva3 Miguel Souza de Andrade4 Valéria Magro Octaviano Bernis1 Walter Octaviano Bernis Filho1 Giliane Souza de Trindade5 George Rego Albuquerque6 Anaiá Paixão da Sevá6 Bergmann Morais Ribeiro4 Danilo Simonini Teixeira6 Fabrício Souza Campos7 Ana Cláudia Franco8 Paulo Michel Roehe8 Danilo Bretas de Oliveira9
Affiliations 9 institutions
  1. Insect Behavior Laboratory, Instituto Federal do Norte de Minas Gerais, Salinas, MG, 39560-000, Brazil.
  2. Medical School, Health Science Post-Graduate Program, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Campus JK - Rodovia MGT 367 - Km 583, n° 5000 - Alto da Jacuba, Diamantina, MG, 39100-000, Brazil.
  3. Centro Estadual de Vigilância em Saúde, Secretaria de Saúde do Rio Grande do Sul, Porto Alegre, RS, 90450-190, Brazil.
  4. Cell Biology Department, Biology Institute, Universidade de Brasília, Brasília, 70910-900, Brazil.
  5. Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil.
  6. Department of Agricultural and Environmental Sciences, State University of Santa Cruz, Ilhéus, BA, 45662-900, Brazil.
  7. Laboratory of Bioinformatics and Biotechnology, Universidade Federal de Tocantins, Gurupi, TO, 77402-970, Brazil.
  8. Laboratório de Virologia, Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, 90050-170, Brazil.
  9. Medical School, Health Science Post-Graduate Program, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Campus JK - Rodovia MGT 367 - Km 583, n° 5000 - Alto da Jacuba, Diamantina, MG, 39100-000, Brazil. [email protected].
PMID34843021 DOI10.1007/s10393-021-01569-1 Year2021 Journal EcoHealth Ecohealth Languageeng Statusppublish

Abstract

In 2019, a new coronavirus disease (COVID-19) was detected in China. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was capable to infect domestic and captive mammals like cats, tigers and minks. Due to genetic similarities, concern about the infection of non-human primates (NHPs) and the establishment of a sylvatic cycle has grown in the Americas. In this study, neotropical primates (NP) were sampled in different areas from Brazil to investigate whether they were infected by SARS-CoV-2. A total of 89 samples from 51 NP of four species were examined. No positive samples were detected via RT-qPCR, regardless of the NHP species, tissue or habitat tested. This work provides the first report on the lack of evidence of the circulation of SARS-CoV-2 in NP. The expansion of wild animals sampling is necessary to understand their role in the epidemiology of SARS-CoV-2 and other potentially zoonotic pathogens in natural environments shared by humans.

Supporting text Virus Host Location
Alouatta 2 Callithrix 7 Coronavirus 195 nonhuman-primate 1 spillback 11 spillover 105 COVID-19 425 Pandemics 108 Animals 1948 Brazil 50 Humans 1440 Primates 28 SARS-CoV-2 453

Evidence records

1 total
Zoonotic Surveillance
1 records · 1 evidence types
Evidence type Viral Detection
1 records
OVE5407 Viral Detection
Key finding

SARS-CoV-2 RNA was not detected by RT-qPCR in neotropical primates sampled in Brazil.

Virus
Severe acute respiratory syndrome coronavirus 2
Host
New World monkeys Platyrrhini Natural host Primates Natural host
Location
Brazil
Supporting text

In this study, neotropical primates (NP) were sampled in different areas from Brazil to investigate whether they were infected by SARS-CoV-2. No positive samples were detected via RT-qPCR, regardless of the NHP species, tissue or habitat tested.

Method
RT-qPCR
Sample type
tissue samples
Geographic raw
Brazil | Minas Gerais | Rio Grande do Sul
Country inferred
BRA