Literature detail

Spread of Canine Influenza A(H3N2) Virus, United States.

Ian E H Voorhees Amy L Glaser Kathy Toohey-Kurth Sandra Newbury Benjamin D Dalziel Edward J Dubovi Keith Poulsen Christian Leutenegger Katriina J E Willgert Laura Brisbane-Cohen Jill Richardson-Lopez Edward C Holmes Colin R Parrish
PMID 28858604 2017 Emerg Infect Dis eng ppublish
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Article

Publication summary

A canine influenza A(H3N2) virus emerged in the United States in February-March 2015, causing respiratory disease in dogs. The virus had previously been circulating among dogs in Asia, where it originated through the transfer of an avian-origin influenza virus around 2005 and continues to circulate. Sequence analysis suggests the US outbreak was initiated by a single introduction, in Chicago, of an H3N2 canine influenza virus circulating among dogs in South Korea in 2015. Despite local control measures, the virus has continued circulating among dogs in and around Chicago and has spread to several other areas of the country, particularly Georgia and North Carolina, although these secondary outbreaks appear to have ended within a few months. Some genetic variation has accumulated among the US viruses, with the appearance of regional-temporal lineages. The potential for interspecies transmission and zoonotic events involving this newly emerged influenza A virus is currently unknown.

canine influenza virus Chicago CIV dog influenza H3N2 Illinois influenza influenza virus outbreak South Korea United States viruses zoonoses Disease Outbreaks Genome, Viral Animals Chicago Dog Diseases

Structured evidence records

Evidence records

3 total
1 records
Extraction confidence 0.95
Key finding

An avian-origin influenza A(H3N2) virus was transmitted from birds to dogs in Asia around 2005, establishing sustained circulation in canine populations.

Virus
Location
Supporting text

The virus had previously been circulating among dogs in Asia, where it originated through the transfer of an avian-origin influenza virus around 2005 and continues to circulate.

Method
sequence analysis
Study design
phylogenetic analysis
Transmission direction
animal-to-animal
Geographic raw
Asia
1 records
Extraction confidence 0.90
Key finding

Genomic sequencing revealed a single introduction of canine influenza A(H3N2) virus from South Korea and subsequent evolutionary diversification into regional-temporal lineages in the United States dog population.

Virus
Location
Not specified
Supporting text

Sequence analysis suggests the US outbreak was initiated by a single introduction, in Chicago, of an H3N2 canine influenza virus circulating among dogs in South Korea in 2015. Some genetic variation has accumulated among the US viruses, with the appearance of regional-temporal lineages.

Genes or proteins
whole genome
Analysis methods
sequence analysis; phylogenetic analysis
1 records
Extraction confidence 0.95
Key finding

A single introduction of H3N2 canine influenza virus from South Korea caused outbreaks in dogs in Chicago and subsequent spread to other US states.

Virus
Location
Supporting text

Sequence analysis suggests the US outbreak was initiated by a single introduction, in Chicago, of an H3N2 canine influenza virus circulating among dogs in South Korea in 2015. Despite local control measures, the virus has continued circulating among dogs in and around Chicago and has spread to several other areas of the country, particularly Georgia and North Carolina.

Method
Sequence analysis
Transmission direction
animal-to-animal
Geographic raw
Chicago; Georgia; North Carolina; United States
Country inferred
United States
Outbreak time
February-March 2015