Bidirectional Human-Swine Transmission of Seasonal Influenza A(H1N1)pdm09 Virus in Pig Herd, France, 2018.
Amélie Chastagner
Vincent Enouf
David Peroz
Séverine Hervé
Pierrick Lucas
Stéphane Quéguiner
Stéphane Gorin
Véronique Beven
Sylvie Behillil
Philippe Leneveu
Emmanuel Garin
Yannick Blanchard
Sylvie van der Werf
Gaëlle Simon
In 2018, a veterinarian became sick shortly after swabbing sows exhibiting respiratory syndrome on a farm in France. Epidemiologic data and genetic analyses revealed consecutive human-to-swine and swine-to-human influenza A(H1N1)pdm09 virus transmission, which occurred despite some biosecurity measures. Providing pig industry workers the annual influenza vaccine might reduce transmission risk.
In 2018, a veterinarian became sick shortly after swabbing sows exhibiting respiratory syndrome on a farm in France. Epidemiologic data and genetic analyses revealed consecutive human-to-swine and swine-to-human influenza A(H1N1)pdm09 virus transmission, which occurred despite some biosecurity measures.
Method
Epidemiologic data; genetic analyses
Transmission direction
animal-to-human
Geographic raw
France
Country inferred
France
Outbreak setting
farm
Outbreak time
2018
Outbreak InvestigationExtraction confidence 0.90
Key finding
Swine on the farm were infected via human-to-swine transmission of influenza A(H1N1)pdm09.
Epidemiologic data and genetic analyses revealed consecutive human-to-swine and swine-to-human influenza A(H1N1)pdm09 virus transmission, which occurred despite some biosecurity measures.
Method
Epidemiologic data; genetic analyses
Transmission direction
human-to-animal
Geographic raw
France
Country inferred
France
Outbreak setting
farm
Outbreak time
2018
Spillover Event2 records
Spillover EventExtraction confidence 0.98
Key finding
Swine-to-human transmission of Influenza A(H1N1)pdm09 virus occurred in France in 2018, infecting a veterinarian after contact with sick pigs.
Epidemiologic data and genetic analyses revealed consecutive human-to-swine and swine-to-human influenza A(H1N1)pdm09 virus transmission on a farm in France.
Method
epidemiologic data; genetic analyses
Study design
outbreak investigation
Transmission direction
animal-to-human
Geographic raw
France
Country inferred
France
Spillover EventExtraction confidence 0.98
Key finding
Human-to-swine transmission of Influenza A(H1N1)pdm09 virus occurred on a farm in France in 2018.
Epidemiologic data and genetic analyses revealed consecutive human-to-swine and swine-to-human influenza A(H1N1)pdm09 virus transmission on a farm in France.
Method
epidemiologic data; genetic analyses
Study design
outbreak investigation
Transmission direction
human-to-animal
Geographic raw
France
Country inferred
France
Genomic Evolution1 records
Genomic EvolutionExtraction confidence 0.72
Key finding
Genetic analyses showed that human and swine influenza A(H1N1)pdm09 viruses in France were closely related, supporting consecutive bidirectional transmission between humans and pigs.
; European Influenza Surveillance Network (EISN). Influenza season 2013/14 has started in Europe with influenza A(H1)pdm09 virus being the most prevalent subtype
; ESNIP3 consortium. European surveillance network for influenza in pigs: surveillance programs, diagnostic tools and Swine influenza virus subtypes identified in 14 European countries from 2010 to 2013
Spatiotemporal distribution and evolution of the A/H1N1 2009 pandemic influenza virus in pigs in France from 2009 to 2017: identification of a potential swine-specific lineage
Chastagner
2018
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National Network for Surveillance of Type A Influenza Virus in Swine (RÉSAVIP). Review of operations and surveillance results for 2016 [in French]
; Flu Watch Group; Combating Swine Influenza (COSI) Consortium. Increased risk of A(H1N1)pdm09 influenza infection in UK pig industry workers compared to a general population cohort
