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Literature detail

SARS-CoV-2 delta variant infection in domestic dogs and cats, Thailand.

Waleemas Jairak1,2,3 Ekkapat Chamsai1,2 Kitikhun Udom1,2 Kamonpan Charoenkul1,2 Supassama Chaiyawong1,2 Navapon Techakriengkrai1,4 Ratanaporn Tangwangvivat5 Kamol Suwannakarn6 Alongkorn Amonsin7,8
Affiliations 8 institutions
  1. Center of Excellence for Emerging and Re-Emerging Infectious Diseases in Animals, and One Health Cluster, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
  2. Department of Veterinary Public Health, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
  3. Bureau of Research and Conservation, Zoological Park Organization, Bangkok, Thailand.
  4. Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
  5. Coordinating Unit for One Health, Division of Communicable Diseases, Department of Disease Control, Nonthaburi, Thailand.
  6. Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
  7. Center of Excellence for Emerging and Re-Emerging Infectious Diseases in Animals, and One Health Cluster, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand. [email protected].
  8. Department of Veterinary Public Health, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand. [email protected].
PMID 35589808 2022 Sci Rep eng epublish
PubMed DOI Browse context

Article

Publication summary

In June-September 2021, we investigated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections in domestic dogs and cats (n = 225) in Bangkok and the vicinities, Thailand. SARS-CoV-2 was detected in a dog and a cat from COVID-19 positive households. Whole genome sequence analysis identified SARS-CoV-2 delta variant of concern (B.1.617.2). Phylogenetic analysis showed that SARS-CoV-2 isolated from dog and cat were grouped into sublineage AY.30 and AY.85, respectively. Antibodies against SARS-CoV-2 could be detected in both dog (day 9) and cat (day 14) after viral RNA detection. This study raises awareness on spill-over of variant of concern in domestic animals due to human-animal interface. Thus, surveillance of SARS-CoV-2 in domestic pets should be routinely conducted.

Cat Diseases COVID-19 Dog Diseases Animals Cats Dogs Phylogeny SARS-CoV-2 Thailand SARS-CoV-2 variants

Structured evidence records

Evidence records

8 total
Genomic Evolution 2 records
Genomic Evolution Extraction confidence 0.90
Key finding

Whole genome and phylogenetic analyses identified SARS-CoV-2 delta variant sublineages AY.30 in a dog and AY.85 in a cat from Thailand.

Virus
SARS-CoV-2
Location
Not specified
Supporting text

Whole genome sequence analysis identified SARS-CoV-2 delta variant of concern (B.1.617.2). Phylogenetic analysis showed that SARS-CoV-2 isolated from dog and cat were grouped into sublineage AY.30 and AY.85, respectively.

Genes or proteins
whole genome
Analysis methods
whole genome sequence analysis; phylogenetic analysis
Genomic Evolution Extraction confidence 0.90
Key finding

Whole genome and phylogenetic analyses identified SARS-CoV-2 delta variant sublineage AY.85 in a cat from Thailand.

Virus
SARS-CoV-2
Location
Not specified
Supporting text

Whole genome sequence analysis identified SARS-CoV-2 delta variant of concern (B.1.617.2). Phylogenetic analysis showed that SARS-CoV-2 isolated from dog and cat were grouped into sublineage AY.30 and AY.85, respectively.

Genes or proteins
whole genome
Analysis methods
whole genome sequence analysis; phylogenetic analysis
Serological Evidence 2 records
Serological Evidence Extraction confidence 0.90
Key finding

Serological testing detected antibodies against SARS-CoV-2 in a domestic dog nine days and in a cat fourteen days after viral RNA detection.

Virus
SARS-CoV-2
Location
Not specified
Supporting text

Antibodies against SARS-CoV-2 could be detected in both dog (day 9) and cat (day 14) after viral RNA detection.

Sample type
serum
Serological Evidence Extraction confidence 0.90
Key finding

Serological testing detected antibodies against SARS-CoV-2 in a domestic cat fourteen days after viral RNA detection.

Virus
SARS-CoV-2
Location
Not specified
Supporting text

Antibodies against SARS-CoV-2 could be detected in both dog (day 9) and cat (day 14) after viral RNA detection.

Sample type
serum
Spillover Event 2 records
Spillover Event Extraction confidence 0.95
Key finding

Detection of SARS-CoV-2 delta variant in a dog and cat from COVID-19 positive households indicates human-to-animal spillback.

Virus
SARS-CoV-2
Location
Thailand Thailand
Supporting text

SARS-CoV-2 was detected in a dog and a cat from COVID-19 positive households. Whole genome sequence analysis identified SARS-CoV-2 delta variant of concern (B.1.617.2).

Method
whole genome sequencing; phylogenetic analysis
Study design
field surveillance
Transmission direction
human-to-animal
Geographic raw
Bangkok and the vicinities, Thailand
Country inferred
Thailand
Spillover Event Extraction confidence 0.95
Key finding

Detection of SARS-CoV-2 delta variant in a cat from a COVID-19 positive household indicates human-to-animal spillback.

Virus
SARS-CoV-2
Location
Thailand Thailand
Supporting text

SARS-CoV-2 was detected in a dog and a cat from COVID-19 positive households. Whole genome sequence analysis identified SARS-CoV-2 delta variant of concern (B.1.617.2).

Method
whole genome sequencing; phylogenetic analysis
Study design
field surveillance
Transmission direction
human-to-animal
Geographic raw
Bangkok and the vicinities, Thailand
Country inferred
Thailand
Zoonotic Surveillance 2 records
Zoonotic Surveillance Extraction confidence 0.95
Key finding

SARS-CoV-2 delta variant RNA and antibodies were detected in a domestic dog in Thailand as part of surveillance of pets from COVID-19-positive households.

Virus
SARS-CoV-2
Location
Thailand Thailand
Supporting text

We investigated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections in domestic dogs (n=225) in Bangkok and the vicinities, Thailand. SARS-CoV-2 was detected in a dog from a COVID-19 positive household.

Method
whole genome sequence analysis; phylogenetic analysis; antibody detection
Geographic raw
Bangkok and the vicinities, Thailand
Country inferred
Thailand
Zoonotic Surveillance Extraction confidence 0.95
Key finding

SARS-CoV-2 delta variant RNA and antibodies were detected in a domestic cat in Thailand as part of surveillance of pets from COVID-19-positive households.

Virus
SARS-CoV-2
Location
Thailand Thailand
Supporting text

We investigated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections in domestic cats (n=225) in Bangkok and the vicinities, Thailand. SARS-CoV-2 was detected in a cat from a COVID-19 positive household.

Method
whole genome sequence analysis; phylogenetic analysis; antibody detection
Geographic raw
Bangkok and the vicinities, Thailand
Country inferred
Thailand