OmniVira

SARS-CoV-2 delta variant infection in domestic dogs and cats, Thailand.

Waleemas Jairak1,2,3 Ekkapat Chamsai1,2 Kitikhun Udom1,2 Kamonpan Charoenkul1,2 Supassama Chaiyawong1,2 Navapon Techakriengkrai1,4 Ratanaporn Tangwangvivat5 Kamol Suwannakarn6 Alongkorn Amonsin7,8
Affiliations 8 institutions
  1. Center of Excellence for Emerging and Re-Emerging Infectious Diseases in Animals, and One Health Cluster, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
  2. Department of Veterinary Public Health, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
  3. Bureau of Research and Conservation, Zoological Park Organization, Bangkok, Thailand.
  4. Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
  5. Coordinating Unit for One Health, Division of Communicable Diseases, Department of Disease Control, Nonthaburi, Thailand.
  6. Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
  7. Center of Excellence for Emerging and Re-Emerging Infectious Diseases in Animals, and One Health Cluster, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand. [email protected].
  8. Department of Veterinary Public Health, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand. [email protected].
PMID35589808 DOI10.1038/s41598-022-12468-y Year2022 Journal Scientific reports Sci Rep Languageeng Statusepublish

Abstract

In June-September 2021, we investigated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections in domestic dogs and cats (n = 225) in Bangkok and the vicinities, Thailand. SARS-CoV-2 was detected in a dog and a cat from COVID-19 positive households. Whole genome sequence analysis identified SARS-CoV-2 delta variant of concern (B.1.617.2). Phylogenetic analysis showed that SARS-CoV-2 isolated from dog and cat were grouped into sublineage AY.30 and AY.85, respectively. Antibodies against SARS-CoV-2 could be detected in both dog (day 9) and cat (day 14) after viral RNA detection. This study raises awareness on spill-over of variant of concern in domestic animals due to human-animal interface. Thus, surveillance of SARS-CoV-2 in domestic pets should be routinely conducted.

Supporting text Virus Host Location
Cat Diseases 67 COVID-19 425 Dog Diseases 65 Animals 1948 Cats 120 Dogs 176 Phylogeny 805 SARS-CoV-2 453 Thailand 21 SARS-CoV-2 variants 86

Evidence records

9 total
Zoonotic Surveillance
6 records · 3 evidence types
Evidence type Virus Isolation
2 records
Evidence type Viral Detection
2 records
OVE5951 Viral Detection
Key finding

SARS-CoV-2 viral RNA was detected in a domestic dog from a COVID-19 positive household in Bangkok, Thailand.

Virus
Severe acute respiratory syndrome coronavirus 2
Host
dog Canis lupus familiaris Natural host
Location
Thailand
Supporting text

In June-September 2021, we investigated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections in domestic dogs and cats (n = 225) in Bangkok and the vicinities, Thailand. SARS-CoV-2 was detected in a dog and a cat from COVID-19 positive households.

Method
viral RNA detection | whole genome sequencing
Sample type
swab samples
Geographic raw
Bangkok | Thailand
Country inferred
THA
OVE5952 Viral Detection
Key finding

SARS-CoV-2 viral RNA was detected in a domestic cat from a COVID-19 positive household in Bangkok, Thailand.

Virus
Severe acute respiratory syndrome coronavirus 2
Host
domestic cat Felis catus Natural host
Location
Thailand
Supporting text

In June-September 2021, we investigated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections in domestic dogs and cats (n = 225) in Bangkok and the vicinities, Thailand. SARS-CoV-2 was detected in a dog and a cat from COVID-19 positive households.

Method
viral RNA detection | whole genome sequencing
Sample type
swab samples
Geographic raw
Bangkok | Thailand
Country inferred
THA
Evidence type Serological Evidence
2 records
Transmission Evidence
2 records · 1 evidence types
Evidence type Cross-species Transmission
2 records
OVE5958 Cross-species Transmission
Key finding

SARS-CoV-2 Delta variant was detected in a dog from a COVID-19 positive household in Bangkok, Thailand, indicating human-to-animal transmission.

Virus
Severe acute respiratory syndrome coronavirus 2
Host
dog Canis lupus familiaris Natural host human Homo sapiens Natural host
Location
Thailand
Supporting text

In June-September 2021, we investigated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections in domestic dogs and cats (n = 225) in Bangkok and the vicinities, Thailand. SARS-CoV-2 was detected in a dog from COVID-19 positive households. Whole genome sequence analysis identified SARS-CoV-2 delta variant of concern (B.1.617.2).

Method
viral RNA detection | whole genome sequencing
Study design
household surveillance study
Transmission direction
human-to-animal
Geographic raw
Bangkok | Thailand
OVE5959 Cross-species Transmission
Key finding

SARS-CoV-2 Delta variant was detected in a cat from a COVID-19 positive household in Bangkok, Thailand, indicating human-to-animal transmission.

Virus
Severe acute respiratory syndrome coronavirus 2
Host
domestic cat Felis catus Natural host human Homo sapiens Natural host
Location
Thailand
Supporting text

In June-September 2021, we investigated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections in domestic dogs and cats (n = 225) in Bangkok and the vicinities, Thailand. SARS-CoV-2 was detected in a cat from COVID-19 positive households. Whole genome sequence analysis identified SARS-CoV-2 delta variant of concern (B.1.617.2).

Method
viral RNA detection | whole genome sequencing
Study design
household surveillance study
Transmission direction
human-to-animal
Geographic raw
Bangkok | Thailand
Genomic Evolution
1 records · 1 evidence types
Evidence type Phylogenetic Evolution
1 records
OVE5957 Phylogenetic Evolution
Key finding

Phylogenetic analysis grouped SARS-CoV-2 from a dog and a cat into Delta sublineages AY.30 and AY.85, respectively.

Virus
Severe acute respiratory syndrome coronavirus 2
Host
dog Canis lupus familiaris Natural host domestic cat Felis catus Natural host
Location
Not specified
Supporting text

Phylogenetic analysis showed that SARS-CoV-2 isolated from dog and cat were grouped into sublineage AY.30 and AY.85, respectively.

Genes or proteins
whole genome
Analysis methods
phylogenetic analysis | whole genome sequence analysis