OmniVira

Literature detail

Distribution and genetic characterization of hantaviruses in bats and rodents from Yunnan.

Yutong Hou1 Qian Li1,2 Xingyu Huang1 Jiale Wang1 Junjie Hou1 Yunze Sun1 Xinrui Wu1 Ziqin Dian3 Binghui Wang4 Xueshan Xia1,4
Affiliations 4 institutions
  1. Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, P.R. China.
  2. Dali University, Dali, P.R. China.
  3. Department of Clinical Laboratory, The First People's Hospital of Yunnan Province, Yunnan, P.R. China.
  4. School of Public Health, Kunming Medical University, Kunming, China.
PMID 39208380 2024 PLoS Negl Trop Dis eng epublish
PubMed DOI Browse context

Article

Publication summary

Hemorrhagic fever with renal syndrome caused by hantaviruses has long been a serious public health issue in Yunnan Province. Hantaviruses exhibit a high extent of biodiversity in their natural hosts, particularly in mammalian hosts. This study was conducted to screen for hantaviruses in bats and rodents in Yunnan Province and elucidate their genetic characteristics and possible zoonotic disease risk. Hantaviruses were detected in 202 bats and 372 rodents with the positive rates 27.49% and 1.25% respectively. A novel lineage (named Lineage 10) of the Seoul virus (SEOV) from rodents and the geographic clustering of hantavirus in bats were identified using phylogenetic analyses of the full-length M- and S-segments. Our study suggest a high cross-species transmissibility of hantaviruses in bats and existence of a new lineage of SEOV in rodents differing significantly from other SEOVs. These results provide data to support the prevention and control of hantavirus-associated diseases in Yunnan Province.

Chiroptera Orthohantavirus Phylogeny Rodentia Animals China Hantavirus Infections Seoul virus

Structured evidence records

Evidence records

5 total
Genomic Evolution 2 records
Genomic Evolution Extraction confidence 0.90
Key finding

Phylogenetic analysis of full-length M- and S-segments identified a novel Seoul virus lineage in rodents and distinct hantavirus clustering in bats, indicating divergent genomic evolution and possible host-associated diversification.

Virus
SEOV
Host
Rodentia
Location
Not specified
Supporting text

A novel lineage (named Lineage 10) of the Seoul virus (SEOV) from rodents and the geographic clustering of hantavirus in bats were identified using phylogenetic analyses of the full-length M- and S-segments.

Genes or proteins
M-segment; S-segment
Analysis methods
phylogenetic analysis
Genomic Evolution Extraction confidence 0.90
Key finding

Phylogenetic analysis indicated geographic clustering of hantaviruses in bats from Yunnan, consistent with lineage-specific evolutionary diversification.

Virus
Hantaviridae
Host
Chiroptera
Location
Not specified
Supporting text

A novel lineage (named Lineage 10) of the Seoul virus (SEOV) from rodents and the geographic clustering of hantavirus in bats were identified using phylogenetic analyses of the full-length M- and S-segments.

Genes or proteins
M-segment; S-segment
Analysis methods
phylogenetic analysis
Zoonotic Surveillance 2 records
Zoonotic Surveillance Extraction confidence 0.95
Key finding

Active surveillance in Yunnan detected hantaviruses in bats with a 27.49% positivity rate, revealing considerable viral diversity and geographic clustering.

Virus
Hantaviridae
Host
Chiroptera
Location
China Yunnan Province, China
Supporting text

This study was conducted to screen for hantaviruses in bats and rodents in Yunnan Province and elucidate their genetic characteristics and possible zoonotic disease risk. Hantaviruses were detected in 202 bats and 372 rodents with the positive rates 27.49% and 1.25% respectively.

Method
screening; phylogenetic analyses
Geographic raw
Yunnan Province
Country inferred
China
Zoonotic Surveillance Extraction confidence 0.95
Key finding

Surveillance in Yunnan identified hantaviruses in rodents, including a novel lineage of Seoul virus distinct from other SEOVs.

Virus
SEOV
Host
Rodentia
Location
China Yunnan Province, China
Supporting text

This study was conducted to screen for hantaviruses in bats and rodents in Yunnan Province and elucidate their genetic characteristics and possible zoonotic disease risk. Hantaviruses were detected in 202 bats and 372 rodents with the positive rates 27.49% and 1.25% respectively.

Method
screening; phylogenetic analyses
Geographic raw
Yunnan Province
Country inferred
China
Cross Species Transmission 1 records
Cross Species Transmission Extraction confidence 0.85
Key finding

Hantaviruses showed high cross-species transmissibility among bats in Yunnan Province, indicating viral transmission between different bat species.

Virus
Hantaviridae
Location
China Yunnan Province, China
Supporting text

Our study suggest a high cross-species transmissibility of hantaviruses in bats and existence of a new lineage of SEOV in rodents differing significantly from other SEOVs.

Method
phylogenetic analysis; screening
Study design
phylogenetic analysis
Transmission direction
animal-to-animal
Geographic raw
Yunnan Province
Country inferred
China