Literature detail

Genetic characterization and receptor binding analysis of a novel H5N1 HPAI virus with a H6Nx-derived PA gene in Guangdong, China.

Jieheng He1 Jing Liu1 Zhanfei Yan1 Gaojie Chen1 Runzhi Liu1 Yu Yang1 Yulin Yan1 Sheng Yuan1 Jinyue Guo1 Yong Li2 Hai Yu3 Zhaoping Liang4 Tao Ren4 Shujian Huang1 Feng Wen1
Affiliations 4 institutions
  1. College of Animal Science and Technology, Foshan University, No. 33 Guangyun Road, Shishan Town, Nanhai District, 528231, Foshan, Guangdong, People's Republic of China.
  2. College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, People's Republic of China.
  3. Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, People's Republic of China.
  4. College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong, People's Republic of China.
PMID 39435481 2024 Emerg Microbes Infect eng ppublish
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Article

Publication summary

No abstract text is available for this record.

Avian influenza virus (AIV) H5N1 H6 subtype highly pathogenic avian influenza virus (HPAIV) PA gene

Structured evidence records

Evidence records

3 total
1 records
Extraction confidence 0.80
Key finding

A novel H5N1 highly pathogenic avian influenza virus from Guangdong possesses a PA gene derived from an H6Nx virus, demonstrating reassortment between H5 and H6 subtypes.

Virus
Host
Not specified
Location
Not specified
Supporting text

Genetic characterization of a novel H5N1 HPAI virus with a H6Nx-derived PA gene in Guangdong, China.

Genes or proteins
PA gene
Analysis methods
genetic characterization
1 records
Extraction confidence 0.80
Key finding

The study analyzed receptor binding of a novel H5N1 highly pathogenic avian influenza virus identified in Guangdong, China.

Virus
Host
Not specified
Location
Not specified
Supporting text

The title states 'receptor binding analysis of a novel H5N1 HPAI virus', indicating experimental evaluation of receptor usage for this virus.

Method
receptor binding analysis
1 records
Extraction confidence 0.90
Key finding

A novel H5N1 highly pathogenic avian influenza virus in Guangdong, China contains a PA gene originating from an H6Nx virus, demonstrating reassortment between H5N1 and H6Nx viruses.

Host
Not specified
Location
Not specified
Supporting text

A novel H5N1 HPAI virus with a H6Nx-derived PA gene was identified in Guangdong, China.

Event type
reassortment
Genes or segments
PA gene