OmniVira

Experimental infection and natural contact exposure of dogs with avian influenza virus (H5N1).

Matthias Giese1 Timm C Harder Jens P Teifke Robert Klopfleisch Angele Breithaupt Thomas C Mettenleiter Thomas W Vahlenkamp
Affiliations 1 institutions
  1. Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
PMID18258127 DOI10.3201/eid1402.070864 Year2008 Journal Emerging infectious diseases Emerg Infect Dis Languageeng Statusppublish

Abstract

Experiments that exposed influenza virus (H5N1)-infected cats to susceptible dogs did not result in intraspecies or interspecies transmission. Infected dogs showed increased body temperatures, viral RNA in pharyngeal swabs, and seroconversion but not fatal disease.

Supporting text Virus Host Location
Animals 1949 Cat Diseases 67 Cats 120 Disease Transmission, Infectious 22 Dog Diseases 65 Dogs 177 Influenza A Virus, H5N1 Subtype 300 Orthomyxoviridae Infections 228 Pharynx 3 RNA, Viral 193

Evidence records

2 total
Zoonotic Surveillance
1 records · 1 evidence types
Evidence type Viral Detection
1 records
OVE531 Viral Detection
Key finding

Viral RNA of avian influenza virus (H5N1) was detected in pharyngeal swabs from infected dogs.

Virus
Influenza A virus H5N1
Host
dog Canis lupus familiaris Experimental system
Location
Not specified
Supporting text

Experiments that exposed influenza virus (H5N1)-infected cats to susceptible dogs did not result in intraspecies or interspecies transmission. Infected dogs showed increased body temperatures, viral RNA in pharyngeal swabs, and seroconversion but not fatal disease.

Method
detection of viral RNA
Sample type
pharyngeal swabs
Experimental Infection
1 records · 1 evidence types
Evidence type Host Range Experiment
1 records
OVE529 Host Range Experiment
Key finding

Dogs experimentally infected with avian influenza virus (H5N1) became infected but did not develop fatal disease.

Virus
Influenza A virus H5N1
Host
dog Canis lupus familiaris Experimental system birds Aves Experimental system
Location
Not specified
Supporting text

Experiments that exposed influenza virus (H5N1)-infected cats to susceptible dogs did not result in intraspecies or interspecies transmission. Infected dogs showed increased body temperatures, viral RNA in pharyngeal swabs, and seroconversion but not fatal disease.

Method
experimental infection | viral RNA detection (RT-PCR) | serology
Sample type
pharyngeal swabs
Experimental system
animal infection model