Highly Pathogenic Avian Influenza A(H5N1) Viruses from Multispecies Outbreak, Argentina, August 2023.

Agustina Rimondi Ralph E T Vanstreels Valeria Olivera Agustina Donini Martina Miqueo Lauriente Marcela M Uhart

Abstract

We report full-genome characterization of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus from an outbreak among sea lions (August 2023) in Argentina and possible spillover to fur seals and terns. Mammalian adaptation mutations in virus isolated from marine mammals and a human in Chile were detected in mammalian and avian hosts.

Supporting text Virus Host Location
Argentina 5 highly pathogenic avian influenza virus H5N1 1 HPAI H5N1 6 influenza 61 mammalian adaptation 4 mammals 99 pinnipeds 4 seabirds 4 South America 8 transmission 55 viruses 117 Influenza A virus 186 Influenza A Virus, H5N1 Subtype 300 Influenza in Birds 341 Animals 1948 Argentina 5 Birds 212 Disease Outbreaks 170 Humans 1440 Mammals 92 Phylogeny 805

Evidence records

1 total
Transmission Evidence
1 records · 1 evidence types
Evidence type
1 records
OVE7826
Key finding

An outbreak of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b occurred among sea lions in Argentina in August 2023.

Virus
Host
Location
Supporting text

We report full-genome characterization of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus from an outbreak among sea lions (August 2023) in Argentina.

Method
full-genome characterization
Transmission direction
same-species transmission
Geographic raw
Argentina
Country inferred
ARG
Outbreak time
August 2023