State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China. Electronic address: [email protected].
Department of Biostatistics and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China. Electronic address: [email protected].
Novel highly pathogenic avian influenza (HPAI) H7N9 viruses of the fifth epidemic wave infect humans and poultry. Recently, HPAI H7N9 viruses have evolved into different subtypes and genotypes, exhibited heightened virulence in mammals, and extended their host range, thereby posing a potential threat to public health and the poultry industry.
evolutionH7N9 virusinfluenza A viruspathogenicitytransmissibilityAnimalsEpidemicsEvolution, MolecularGenotypeHost SpecificityHumansInfluenza A Virus, H7N9 SubtypeInfluenza in BirdsInfluenza, HumanOrthomyxoviridae InfectionsPoultryPublic HealthVirulence
Structured evidence records
Evidence records
4 total
Cross Species Transmission1 records
Cross Species TransmissionExtraction confidence 0.75
Key finding
Highly pathogenic avian H7N9 influenza viruses expanded from avian sources to infect mammalian hosts, showing cross-species transmission among non-human animals.
HPAI H7N9 viruses have evolved into different subtypes and genotypes, exhibited heightened virulence in mammals, and extended their host range.
Transmission direction
animal-to-animal
Genomic Evolution1 records
Genomic EvolutionExtraction confidence 0.80
Key finding
Highly pathogenic H7N9 influenza viruses have undergone genetic evolution into distinct subtypes and genotypes, associated with increased virulence and expanded host range.
Recently, HPAI H7N9 viruses have evolved into different subtypes and genotypes, exhibited heightened virulence in mammals, and extended their host range. MeSH terms include 'Influenza A Virus, H7N9 Subtype / genetics' and 'Evolution, Molecular'.
Novel highly pathogenic avian influenza (HPAI) H7N9 viruses of the fifth epidemic wave infect humans and poultry. Recently, HPAI H7N9 viruses have evolved into different subtypes and genotypes, exhibited heightened virulence in mammals, and extended their host range.
