Seroprevalence of Influenza A(H5N1) Virus in Domestic Cats at Epicenter of Dairy Cattle Outbreaks, California, USA, 2024-2026.

Ian G Bemis Ismaila Shittu Jacob F Gomez Esther A Fadaka Sofia Perez Gregory C Gray Kristen K Coleman

Abstract

We conducted a serologic study of domestic cats near the epicenter of the dairy cattle outbreaks of influenza A(H5N1) in California, USA. Three of the 12 cats sampled within 2 km of farms had neutralizing antibodies against H5N1 virus. Proximity to dairy farms was a statistically significant risk factor for seropositivity.

Supporting text Virus Host Location
avian influenza virus 59 California 6 cats 133 cross-species transmission 75 dairy cattle 3 H5N1 82 influenza 61 One Health 98 United States 56 viruses 117 zoonoses 477

Evidence records

2 total
Zoonotic Surveillance
2 records · 2 evidence types
Evidence type
1 records
OVE11912
Key finding

Neutralizing antibodies to H5N1 were detected in 3 of 12 domestic cats sampled within 2 km of dairy farms in California, USA.

Virus
Host
Location
Not specified
Supporting text

Three of the 12 cats sampled within 2 km of farms had neutralizing antibodies against H5N1 virus.

Method
neutralization assay | serologic study
Sample type
serum
Evidence type
1 records
OVE11913
Key finding

Among domestic cats in California, proximity to dairy farms was a significant ecological risk factor associated with H5N1 seropositivity.

Virus
Host
Location
Supporting text

We conducted a serologic study of domestic cats near the epicenter of the dairy cattle outbreaks of influenza A(H5N1) in California, USA. Proximity to dairy farms was a statistically significant risk factor for seropositivity.

Method
serologic study | neutralization assay | risk factor analysis
Sample type
serum | neutralizing antibodies
Geographic raw
California, USA
Country inferred
USA