OmniVira

Complete genome sequence of an avian-like H4N8 swine influenza virus discovered in southern China.

Shuo Su1 Wen-Bao Qi Ji-Dang Chen Nan Cao Wan-Jun Zhu Li-Guo Yuan Heng Wang Gui-Hong Zhang
Affiliations 1 institutions
  1. College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, China.
PMID22879613 DOI10.1128/JVI.01475-12 Year2012 Journal Journal of virology J Virol Languageeng Statusppublish

Abstract

We report here the complete genomic sequence of an avian-like H4N8 swine influenza virus containing an H5N1 avian influenza virus segment from swine in southern China. Phylogenetic analyses of the sequences of all eight viral RNA segments demonstrated that these are wholly avian influenza viruses of the Asia lineage. To our knowledge, this is the first report of interspecies transmission of an avian H4N8 influenza virus to domestic pigs under natural conditions.

Supporting text Virus Host Location
Genome, Viral 317 Animals 1948 Base Sequence 52 China 229 Influenza A virus 186 Molecular Sequence Data 160 Orthomyxoviridae Infections 228 Phylogeny 805 Swine 258 Swine Diseases 153

Evidence records

3 total
Zoonotic Surveillance
1 records · 1 evidence types
Evidence type Viral Detection
1 records
OVE1259 Viral Detection
Key finding

Avian-like H4N8 influenza virus containing an H5N1 segment was detected in swine from southern China.

Virus
Influenza A virus H4N8 Influenza A virus H5N1
Host
pig Sus scrofa Natural host
Location
China
Supporting text

We report here the complete genomic sequence of an avian-like H4N8 swine influenza virus containing an H5N1 avian influenza virus segment from swine in southern China.

Method
complete genomic sequencing | phylogenetic analysis
Sample type
swine samples
Geographic raw
southern China
Country inferred
CHN
Transmission Evidence
1 records · 1 evidence types
Evidence type Cross-species Transmission
1 records
OVE1261 Cross-species Transmission
Key finding

An avian H4N8 influenza virus was transmitted from avian hosts to domestic pigs under natural conditions in southern China.

Virus
Influenza A virus H4N8
Host
domestic pig Sus scrofa domesticus Natural host birds Aves Natural host
Location
China
Supporting text

We report here the complete genomic sequence of an avian-like H4N8 swine influenza virus containing an H5N1 avian influenza virus segment from swine in southern China. To our knowledge, this is the first report of interspecies transmission of an avian H4N8 influenza virus to domestic pigs under natural conditions.

Method
genomic sequencing | phylogenetic analysis
Study design
phylogenetic analysis and genome sequencing report
Transmission direction
animal-to-animal
Geographic raw
southern China
Genomic Evolution
1 records · 1 evidence types
Evidence type Phylogenetic Evolution
1 records
OVE1260 Phylogenetic Evolution
Key finding

Phylogenetic analysis indicated that all eight RNA segments of the H4N8 swine influenza virus are avian-origin belonging to the Asia lineage.

Virus
Influenza A virus H4N8
Host
pig Sus scrofa Natural host
Location
Not specified
Supporting text

We report here the complete genomic sequence of an avian-like H4N8 swine influenza virus containing an H5N1 avian influenza virus segment from swine in southern China. Phylogenetic analyses of the sequences of all eight viral RNA segments demonstrated that these are wholly avian influenza viruses of the Asia lineage.

Genes or proteins
eight viral RNA segments
Analysis methods
phylogenetic analyses